Ying Wang 王穎

Associate Professor

  1. Shao-Ru Chen, Zheng-Qing Li, Jun Xu, Mo-Yu Ding, Yaming Shan, Yung-Chi Cheng, Gao-Xiao Zhang, Ye-Wei Sun, Yu-Qiang Wang, Ying Wang*. Celastrol attenuates hepatitis C virus translation and inflammatory response in mice by suppressing heat shock protein 90β. Acta Pharmacologica Sinica, 2023, https://doi.org/10.1038/s41401-023-01067-w.
  2. Mo-Yu Ding, Yuran Peng, Feng Li, Zheng-Qing Li, Decai Wang, Guo-Chun Zhou, Ying Wang*. Andrographolide derivative as antagonist of vitamin D receptor to induce lipidation of microtubule associate protein 1 light chain 3 (LC3). Bioorganic & Medicinal Chemistry, 51: 116505, 2021.
  3. Zheng-Qing Li, Xiu-Ping Chen*, Ying Wang*. Small molecules targeting ubiquitination to control inflammatory diseases. Drug Discovery Today, 26: 2414-2422, 2021.
  4. Qiu-Ling Chen#, Hao-Ran Yin#, Qing-Yu He*, Ying Wang*. Targeting the NLRP3 inflammasome as new therapeutic avenue for inflammatory bowel disease. Biomedicine & Pharmacotherapy, 138: 111442, 2021.
  5. Bin Xu, Mo-Yu Ding, Zhibing Weng, Zheng-Qing Li, Feng Li, Xia Sun, Qiu-Ling Chen, Yitao Wang, Ying Wang*, Guo-Chun Zhou*. Discovery of fused bicyclic derivatives of 1H-pyrrolo[1,2-c]imidazol-1-one as VDR signaling regulators. Bioorganic & Medicinal Chemistry, 27: 3879, 2019.
  6. Shen-Fei Wang, Xin Liu, Mo-Yu Ding, Shuangcheng Ma, Jing Zhao*, Ying Wang*, Shaoping Li*. 2-O-β-D-Glucopyranosyl-L-ascorbic acid, a novel vitamin C derivative from Lycium barbarum, prevents oxidative stress. Redox Biology, 24: 101173, 2019.
  7. Bao-Jian Guo#, Zhuyun Liu, Mo-Yu Ding#, Feng Li, Mei Jing, Li-Peng Xu, Yu-Qiang Wang, Zai-Jun Zhang, Yitao Wang, Decai Wang, Guo-Chun Zhou*, Ying Wang*. Andrographolide derivative ameliorates dextran sulfate sodium-induced experimental colitis in mice. Biochemical Pharmacology, 163: 416-424, 2019.
  8. Chao Zhao, Jinlin Fan, Yuanyuan Liu, Weiling Guo, Hui Cao, Jianbo Xiao, Ying Wang*, Bin Liu*. Hepatoprotective activity of Ganoderma lucidum triterpenoids in alcohol-induced liver injury in mice, an iTRAQ-based proteomic analysis. Food Chemistry, 271:148-156, 2019.
  9. Ying Wang, Yaming Shan, Xinyu Gao, Rui Gong, Jun Zheng, Xiaohua Douglas Zhang, Qi Zhao*. Screening and expressing HIV-1 specific antibody fragments in Saccharomyces cerevisiae. Molecular Immunology, 103: 279-285, 2018.
  10. Shao-Ru Chen#, Feng Li#, Mo-Yu Ding, Decai Wang, Qi Zhao, Yitao Wang, Guo-Chun Zhou, Ying Wang*. Andrographolide Derivative as STAT3 Inhibitor that Protects Acute Liver Damage in Mice. Bioorganic & Medicinal Chemistry, 26: 5053-5061, 2018.
  11. Feng Li#, Xiao-Min Li#, Dekun Sheng, Shao-Ru Chen, Xin Nie, Zhuyun Liu, Decai Wang, Yitao Wang, Qi Zhao, Ying Wang*, Guo-Chun Zhou*. Discovery and preliminary SAR of 14-aryloxy-andrographolide derivatives as antibacterial agents with immunosuppressant activity. RSC Advances, 8: 9440-9456, 2018.
  12. Xian-Qiang Chen, Jing Zhao*, Ling-Xiao Chen, Shen-Fei Wang, Ying Wang*, Shao-Ping Li*. Lanostane triterpenes from the mushroom Ganoderma resinaceum and their inhibitory activities against alpha-glucosidase. Phytochemistry, 149: 103-115, 2018.
  13. Yan Dai#, Shao-Ru Chen#, Ling Chai, Jing Zhao, Yitao Wang*, Ying Wang*. Overview of Pharmacological Activities of Andrographis paniculata and its Major Compound Andrographolide. Critical Reviews in Food Science and Nutrition, 10: 1-13, 2018.
  14. Shao-Ru Chen, Yan Dai, Jing Zhao, Ligen Lin, Yitao Wang*, Ying Wang*. A mechanistic overview of Triptolide and Celastrol: natural products from Tripterygium wilfordii Hook F. Frontiers in Pharmacology, 9: 104, 2018.
  15. Ying Wang, Shao-Ru Chen, Xiaoming Yang, Kuo-Hsiung Lee, Yung-Chi Cheng. Structure-activity relationships of cryptopleurine analogs with E-ring modifications as anti-hepatitis C virus agents. Bioorganic & Medicinal Chemistry, 26: 630-636, 2018.
  16. Min Li, Ling-Xiao Chen, Shao-Ru Chen, Yong Deng, Jing Zhao, Ying Wang*, Shao-Ping Li*. Non-starch polysaccharide from Chinese yam activated RAW 264.7 macrophages through the Toll-like receptor 4 (TLR4)-NF-κB signaling pathway. Journal of Functional Foods, 37: 491-500, 2017.
  17. Ying Wang, Sangwon Lee, Ya Ha, Wing Lam, Shao-Ru Chen, Ginger E. Dutschman, Elizabeth A. Gullen, Susan P. Grill, Yao Cheng, Alois Fürstner, Samson Francis, David C. Baker, Xiaoming Yang, Kuo-Hsiung Lee, and Yung-Chi Cheng*. Tylophorine analogs allosterically regulates heat shock cognate protein 70 and inhibits hepatitis C virus replication. Scientific Reports, 7: 10037, 2017.
  18. Bao-Jian Guo, Zhao-Xiang Bian, Hong-Cong Qiu, Yitao Wang, Ying Wang*. Biological and clinical implications of herbal medicine and natural products for the treatment of inflammatory bowel disease. Annals of the New York Academy of Sciences, 1401: 37-48, 2017.
  19. Xin Nie, Shao-Ru Chen, Kun Wang, Yuran Peng, Yitao Wang, Decai Wang, Ying Wang*, Guo-Chun Zhou*. Attenuation of innate immunity by andrographolide derivatives through NF-κB signaling pathway. Scientific Reports, 7: 4738, 2017.
  20. Lie-Jun Huang#, Shao-Ru Chen#, Chun-Mao Yuan, Wei Gu, Bao-Jian Guo, Yi-Tao Wang, Ying Wang*, Xiao-Jiang Hao*. C21-steroidal pregnane sapogenins and their derivatives as anti-inflammatory agents. Bioorganic & Medicinal Chemistry, 25: 3512-3524, 2017.
  21. Min Li, Yi-Xi Yan, Qing-Tao Yu, Yong Deng, Ding-Tao Wu, Ying Wang, Ya-Zhong Ge, Shao-Ping Li*, Jing Zhao*. Comparison of immunomodulatory effects of fresh garlic and black garlic polysaccharides on RAW 264.7 macrophages. Journal of Food Science, 82: 765-771, 2017.
  22. Ying Wang, Wing Lam, Shao-Ru Chen, Fulan-Guan, Ginger Dutchman, Samson Francis, David Baker, Yung-Chi Cheng*. Tylophorine analog DCB-3503 inhibited cyclin D1 translation through allosteric regulation of heat shock cognate protein 70. Scientific Reports, 6: 32832, 2016.
  23. Shao-Ru Chen, An-Qi Wang, Hong-Cong Qiu, Li-Gen Lin, Yi-Tao Wang*, Ying Wang*. In Vitro Study on Anti-Hepatitis C Virus Activity of Spatholobus suberectus Dunn. Molecules, 21: 1367, 2016.
  24. Shao-Ru Chen, Hong-Cong Qiu, Yang Hu, Ying Wang*, Yi-Tao Wang*. Herbal medicine offered as an initiative therapeutic option for the management of hepatocellular carcinoma. Phytotherapy Research, 30: 863, 2016.
  25. Shao-Ru Chen, Xiu-Ping Chen, Jin-Jian Lu, Ying Wang*, Yi-Tao Wang*. Implications of natural product and herbal medicine for the treatment of liver fibrosis. Chinese Medicine, 10: 7, 2015.
  26. Ying Wang*, Qing-Yu He, Jen-Fu Chiu*. Dioscin induced activation of p38 MAPK and JNK via mitochondrial pathway in HL-60 cell line. European Journal of Pharmacology, 735: 52, 2014.
  27. Ying Wang, Hui-Chyn Wong, Elizabeth A. Gullen, Wing Lam, Xiaoming Yang, Qian Shi, Kuo-Hsiung Lee, Yung-Chi Cheng*. Cryptopleurine analogs with modification of E ring exhibit different mechanism to Rac-cryptopleurine and tylophorine. PLoS ONE, 7: e51138, 2012.
  28. Ying Wang, Wenli Gao, Yuri V. Svitkin, Annie Pei-Chun Chen, Yung-Chi Cheng*. DCB-3503, a tylophorine analog, inhibits protein synthesis through a novel mechanism. PLoS ONE, 5: e11607, 2010.
  29. Ying Wang, Qing-Yu He, Sai-Wah Tsao, Yim-Hing Cheung, Anita Wong, Jen-Fu Chiu*. Cytokeratin 8 silencing in human nasopharyngeal carcinoma cells leads to cisplatin sensitization. Cancer Letters, 265: 188, 2008.
  30. Chi-Chun Wong, Ying Wang, Jen-Fu Chiu, Qing-Yu He*, Feng Chen*. Comparative proteomic analysis of indioside D-triggered cell death in HeLa cells. Journal of Proteome Research, 8: 2420, 2008.
  31. Ying Wang, Qing-Yu He, Chi-Ming Che, Sai Wah Tsao, Raymond Wai-Yin Sun, Jen-Fu Chiu*. Modulation of gold(III) porphyrin 1a-induced apoptosis by mitogen-activated protein kinase signaling pathways. Biochemical Pharmacology, 75: 1282, 2008.
  32. Ying Wang, Jen-Fu Chiu*. Proteomic approaches in understanding action mechanisms of metal-based anticancer drugs. Metal Based Drugs, 2008: 716329, 2008.
  33. Andy T.Y. Lau#, Ying Wang#, Jen-Fu Chiu*. Reactive oxygen species: current knowledge and applications in cancer research and therapeutic. Journal of Cellular Biochemistry, 104: 657-667, 2008.
  34. Ying Wang, Jen-Fu Chiu, Qing-Yu He*. Isolation of cytoplasmic proteins from cultured cells for two-dimensional gel electrophoresis. 2D PAGE: Sample Preparation and Fractionation. Methods in Molecular Biology, 425: 101-112, 2008.
  35. Ying Wang, Chi-Ming Che, Jen-Fu Chiu, Qing-Yu He*. Dioscin (saponin)-induced generation of reactive oxygen species through mitochondria dysfunction: a proteomic-based study. Journal of Proteome Research, 6: 4703, 2007.
  36. Ying Wang, Qing-Yu He, Hongmin Chen, Jen-Fu Chiu*. Synergistic effects of retinoic acid and tamoxifen on human breast cancer cells: proteomic characterization. Experimental Cell Research, 313: 357, 2007.
  37. Ying Wang, Qing-Yu He, Raymond Wai-Yin Sun, Chi-Ming Che*, Jen-Fu Chiu*. Cellular pharmacological properties of gold(III) porphyrin 1a, a potential anticancer drug lead. European Journal of Pharmacology, 554: 113, 2007.
  38. Ying Wang, Yim Hing Cheung, Zhiqi Yang, Jen-Fu Chiu, Chi-Ming Che*, Qing-Yu He*. Proteomic approach to study the cytotoxicity of dioscin (saponin). Proteomics, 6: 2422, 2006.
  39. Ying Wang, Qing-Yu He, Chi-Ming Che*, Jen-Fu Chiu*. Proteomic characterization of the cytotoxic mechanism of gold(III) porphyrin 1a, a potential anticancer drug. Proteomics, 6: 131, 2006.
  40. Ying Wang, Jen-Fu Chiu, Qing-Yu He*. Proteomics approach to illustrate drug action mechanisms. Current Drug Discovery Technologies, 3: 199-209, 2006.
  41. Ying Wang, Qing-Yu He, Raymond Wai-Yin Sun, Chi-Ming Che*, Jen-Fu Chiu*. Gold(III) porphyrin 1a induced apoptosis by mitochondrial death pathways related to reactive oxygen species. Cancer Research, 65: 11553, 2005.
  • The Consortium for Globalization of Chinese Medicine      Member