De Fang OUYANG 歐陽德方

Associate Professor

10 representative publications in recent 3 years

  1. Gao Hanlu, Wang Wei, Dong Jie, Ye Zhuyifan, Defang Ouyang*. An integrated computational methodology with data-driven machine learning, molecular modeling and PBPK modeling to accelerate solid dispersion formulation design. European Journal of Pharmaceutics and Biopharmaceutics, 158 (2021) 336–346;
  2. Yuan He, Zhuyifan Ye, Xinyang Liu, Hai-Feng Li, Ying Zheng, Defang Ouyang*. Can machine learning predict drug nanocrystals? Journal of Controlled Release, 2020, 322, 274-285; (Cover page)
  3. Run Han, Hui Xiong, Zhuyifan Ye, Yilong Yang, Tianhe Huang, Qiufang Jing, Jiahong Lu, Hao Pan, Fuzheng Ren, Defang Ouyang*. Predicting physical stability of solid dispersions by machine learning techniques, Journal of Controlled Release, 2019, 311-312, 16-25; (Cover page)
  4. Qianqian Zhao, Ye Zhuyifang, Yan Su, Defang Ouyang*. Predicting Complexation Performance between Cyclodextrins and Guest Molecules by Integrated Machine learning and Molecular Modeling Techniques. Acta Pharmaceutica Sinica B, 2019, 9(6), 1241-1252;
  5. Conglian Yang, Kun Tu, Hanlu Gao, Liao Zhang, Yu Sun, Ting Yang, Li Kong, Defang Ouyang*, Zhiping Zhang*. The novel platinum(IV) prodrug with self-assembly property and structure-transformable character against triple-negative breast cancer, Biomaterials, 2020, 232, 119751;
  6. Zhuyifan Ye, Yilong Yang, Xiaoshan Li, Dongsheng Cao, Defang Ouyang*. An Integrated Transfer Learning and Multitask Learning Approach for Pharmacokinetic Parameter Prediction. Molecular Pharmaceutics, 2019, 16 (2), 533−541;
  7. Yilong Yang, Zhuyifan Ye, Yan Su, Qianqian Zhao, Xiaoshan Li, Defang Ouyang*. Deep learning for in vitro prediction of pharmaceutical formulations. Acta Pharmaceutica Sinica B, 2019;9(1):177–185;
  8. Hao Zhong, Ging Chan, Hao Hu, Yuanjia Hu, Defang Ouyang*. A comprehensive map on FDA-approved pharmaceutical products. Pharmaceutics, 2018, 10(4), 263;
  9. Tianhe Huang, Qianqian Zhao, Yan Su, Defang Ouyang*. Investigation of Molecular Aggregation Mechanism of Glipizide/Cyclodextrin Complexation by Combined Experimental and Molecular Modeling Approaches. Asian Journal of Pharmaceutical Sciences, 2019, 14(6), 609-620; (cover page)
  10. Weixiang Zhang, Qianqian Zhao, Junling Deng, Yuanjia Hu, Yitao Wang, Defang Ouyang*. Big data analysis of global advances in pharmaceutics and drug delivery from 1980 – 2014. Drug Discovery Today. 2017, 22(8), 1201-1208.
  • Editorial-in-Chief of “In Silico Pharmacology” (Springer);
  • Associate editor of “Drug Delivery and Translational Research”;
  • Editorial board of “Asian Journal of Pharmaceutical Sciences”, “Pharmaceutical Research” and “Pharmaceutics”;
  • Scientific Advisor of “Journal of Pharmaceutical Sciences”;
  • Topic editor of “Pharmaceutics” and “Frontier in Pharmacology”;
  • Fellow of the Higher Education Academy (UK);
  • Grant reviewer of BBSRC (UK) and French National Research Agency (ANR);
  • 2015 Outstanding reviewer of “International Journal of Pharmaceutics”;
  • Reviewer of over 20 SCI journals;
  • Computational Pharmacy Society (CPS)
  • American Chemical Society (ACS)
  • Asian Association of Schools of Pharmacy (AASP)