Anna, Wai San CHEANG 鄭慧珊

Assistant Professor

* co-/corresponding author; co-first author

  1. Miao L, Zhang H, Cheong MS, Zhong R, Garcia-Oliveira P, Prieto MA, Cheng KW, Wang M, Cao H, Nie S, Simal-Gandara J, Cheang WS*, Xiao J. Anti-diabetic potential of apigenin, luteolin, and baicalein via partially activating PI3K/Akt/Glut-4 signaling pathways in insulin-resistant HepG2 cells. Food Science and Human Wellness (2022) In press (Impact factor: 5.154)
  2. Gong G, Kam H; Chen H, Chen Y, Cheang WS, John P. Giesy JP, Zhou Q, Lee SLY. Role of endocrine disruption in toxicity of 6-benzylaminopurine (6-BA) to early-life stages of zebrafish. Ecotoxicology and Environmental Safety (2022) In press (Impact factor: 6.291)
  3. Wu Z, Jayachandran M, Cheang WS, Xu B. Black Truffle Extract Exerts Antidiabetic Effects through Inhibition of Inflammation and Lipid Metabolism Regulation. Oxidative Medicine and Cellular Longevity (2022) In press (Impact factor: 6.543)
  4. Zhou Y, Khan H, Xiao J, Cheang WS*. Effects of Arachidonic Acid Metabolites on Cardiovascular Health and Disease. International Journal of Molecular Sciences (2021) 22(21), 12029 (Impact factor: 5.924)
  5. Alam W, Rocca C, Khan H, Hussain Y, Aschner M, Bartolo A, Amodio N, Angelone T, Cheang WS. Current Status and Future Perspectives on Therapeutic Potential of Apigenin: Focus on Metabolic Syndrome-Dependent Organ Dysfunction. Antioxidants (2021) 10(10), 1643 (Impact factor: 312)
  6. Zhang X, Zhou C, Miao L, Tan Y, Zhou Y, Cheong MS, Huang Y, Wang Y, Yu H, Cheang WS*. Panax Notoginseng Protects against Diabetes-associated Endothelial Dysfunction: Comparison between Ethanolic Extract and Total Saponin. Oxidative Medicine and Cellular Longevity (2021) 2021:4722797 (Impact factor: 6.543)
  7. Zhou C, Zhang X, Ruan CC, Cheang WS*. Two methoxy derivatives of resveratrol, 3,3’,4,5’-tetramethoxy-trans-stilbene and 3,4’,5-trimethoxy-trans-stilbene, suppress lipopolysaccharide-induced inflammation through inactivation of MAPK and NF-κB pathways in RAW 264.7 cells. Chinese Medicine (2021) 16(1):69 (Impact factor: 5.455)
  8. Zhou Y, Murugan DD, Khan H, Huang Y, Cheang WS*. Roles and Therapeutic Implications of Endoplasmic Reticulum Stress and Oxidative Stress in Cardiovascular Diseases. Antioxidants (2021) 10(8), 1167 (Impact factor: 312)
  9. Zhou Y, Zhou C, Zhang X, Vong CT, Wang Y, Cheang WS*. Coptisine attenuates diabetes-associated endothelial dysfunction through inhibition of endoplasmic reticulum stress and oxidative stress. Molecules(2021) 26(14), 4210 (Impact factor: 411)
  10. Khan H, Ullah H, Aschner M, Cheang WS, Akkol EK. Neuroprotective effects of quercetin in Alzheimer’s disease. Biomolecules (2020) 10(1):59 (Impact factor: 879)
  11. Zhong Z, Zhang Q, Tao H, Sang W, Cui L, Qiang W, Cheang WS, Hu Y, Yu H, Wang YT. Anti-inflammatory activities of Sigesbeckia glabrescens Makino: combined in vitro and in silico investigations. Chinese Medicine (2019) 14:35. (Impact factor: 455)
  12. Miao L, Tao H, Peng Y, Wang S, Zhong Z, El-Seedi H, Dragan S, Zengin G, Cheang WS, Wang YT, Xiao J. The anti-inflammatory potential of Portulaca oleracea L. (purslane) extract by partial suppression on NF-B and MAPK activation. Food Chemistry (2019) 290:239-45. (Impact factor: 514)
  13. Li ZX, Zhao GD, Xiong W, Linghu KG, Ma QS, Cheang WS, Yu H, Wang YT. Immunomodulatory effects of a new whole ingredients extract from Astragalus: a combined evaluation on chemistry and pharmacology. Chinese Medicine (2019) 14:12. (Impact factor: 455)
  14. Zhao C, Lai S, Wu Y, Guan Y, Cao H, Cheang WS, Liu B, Zhao K, Miao S, Riviere C, Capanoglu E, Xiao J. Effects of domestic cooking process on the chemical and biological properties of dietary phytochemicals. Trends in Food Science & Technology (2019) 85:55-66 (Impact factor: 12.563)
  15. Cheang WS, Wong WT, Wang L, Cheng CK, Lau CW, Ma RCW, Xu A, Wang N, Huang Y, Tian XY. Resveratrol ameliorates endothelial dysfunction in diabetic and obese mice through sirtuin 1 and peroxisome proliferator-activated receptor δ. Pharmacological Research (2019) 139:384-94 (Impact factor: 7.658)
  16. Zhao C, Yang C, Wai STC, Zhang YB, Portillo MP, Paoli P, Wu Y, Cheang WS, Liu B, Carpene C, Xiao J, Cao H. Regulation of glucose metabolism by bioactive phytochemicals for the management of type 2 diabetes mellitus. Critical Reviews in Food Science and Nutrition (2019) 59(6):830-47 (Impact factor: 176)
  17. Xiong W, Sang W, Linghu KG, Zhong ZF, Cheang WS, Li J, Hu YJ, Yu H, Wang YT (2018) Dual-functional Brij-S20-modified nanocrystal formulation enhances the intestinal transport and oral bioavailability of berberine. International Journal of Nanomedicine (2018) 13:3781-93. (Impact factor: 400)
  18. Sang W, Zhong Z, Linghu K, Xiong W, Tse AKW, Cheang WS, Yu H, Wang Y. Siegesbeckia pubescens Makino inhibits Pam3CSK4-induced inflammation in RAW 264.7 macrophages through suppressing TLR1/TLR2-mediated NF-κB activation. Chinese Medicine (2018) 13:37. (Impact factor: 455)
  19. Chen L, Teng H, Xie Z, Cheang WS, Skalicka-Woniak K, Georgiev MI, Xiao J. Modifications of dietary flavonoids towards improved bioactivity: An update on structure-activity relationship. Critical Reviews in Food Science and Nutrition (2018) 58(4):513-27. (Impact factor: 176)
  20. Cheang WS, Wong WT, Zhao L, Xu J, Wang L, Lau CW, Chen ZY, Ma RCW, Xu A, Wang N, Tian XY, Huang Y. PPARδ is required for exercise to attenuate endoplasmic reticulum stress and endothelial dysfunction in diabetic mice. Diabetes (2017) 66(2):519-28. (Impact factor: 461)
  21. Xiang L, Wei J, Tian XY, Wang B, Chan W, Li S, Tang Z, Zhang H, Cheang WS, Zhao Q, Zhao H, Yang Z, Hong Y, Huang Y, Cai Z. Comprehensive analysis of acylcarnitine species in db/db mouse using a novel method of high-resolution parallel reaction monitoring reveals widespread metabolic dysfunction induced by diabetes. Analytical Chemistry (2017) 89(19):10368-10375. (Impact factor: 986)
  22. Leung FP, Yung LM, Ngai CY, Cheang WS, Tian XY, Lau CW, Zhang Y, Liu J, Chen ZY, Bian ZX, Yao X, Huang Y. Chronic black tea extract consumption improves endothelial function in ovariectomized rats. European Journal of Nutrition (2016) 55:1963-72. (Impact factor: 614)
  23. Zhang Y, Liu J, Luo JY, Tian XY, Cheang WS, Xu J, Lau CW, Wang L, Wong WT, Wong CM, Lan HY, Yao X, Raizada MK, Huang Y. Upregulation of angiotensin (1-7)-mediated signaling preserves endothelial function through reducing oxidative stress in diabetes. Antioxidants & Redox Signaling (2015) 23(11):880-92. (Impact factor: 8.401)
  24. Cheang WS, Tian XY, Wong WT, Huang Y. The peroxisome proliferator-activated receptors in cardiovascular diseases: experimental benefits and clinical challenges. British Journal of Pharmacology (2015) 172(23):5512-22. (Impact factor: 8.739)
  25. Wang X, #Cheang WS, Yang H, Xiao L, Lai B, Zhang M, Ni J, Luo Z, Zhang Z, Huang Y, Wang N. Nuciferine relaxes rat mesenteric arteries through endothelium-dependent and independent mechanisms. British Journal of Pharmacology (2015) 172(23):5609-18. (Impact factor: 8.739)
  26. Cheang WS, Tian XY, Wong WT, Lee SS, Chen ZY, Yao X, Wang N, Huang Y. Metformin protects endothelial function in diet-induced obese mice by inhibition of endoplasmic reticulum stress through 5’ adenosine monophosphate-activated protein kinase-peroxisome proliferator-activated receptor δ pathway. Arteriosclerosis, Thrombosis, and Vascular Biology (2014) 34(4):830-6. (Impact factor: 8.311)
  27. Zhang Y, Liu J, Tian XY, Wong WT, Chen Y, Wang L, Luo JY,Cheang WS, Lau CW, Kwan KM, Wang N, Yao X & Huang Y. Inhibition of bone morphogenic protein-4 restores endothelial function in db/db diabetic mice. Arteriosclerosis, Thrombosis, and Vascular Biology (2014) 34(1):152-9. (Impact factor: 8.311)
  28. Tian XY, Wong WT, Wang N, Lu Y, Cheang WS, Liu J, Liu L, Liu Y, Lee SS, Chen ZY, Cooke JP, Yao X, Huang Y. PPARδ activation protects endothelial function in diabetic mice. Diabetes (2012) 61(12):3285-93. (Impact factor: 9.461)
  29. Tian XY, Wong WT, Xu A, Lu Y, Zhang Y, Wang L, Cheang WS, Wang Y, Yao X, Huang Y. Uncoupling protein-2 protects endothelial function in diet-induced obese mice. Circulation Research (2012) 110(9):1211-6. (Impact factor: 17.367)
  30. Tian XY, Wong WT, Sayed N, Luo J, Tsang SY, Bian ZX, Lu Y, Cheang WS, Yao X, Chen ZY, Huang Y. NaHS relaxes rat cerebral artery in vitro via inhibition of l-type voltage-sensitive Ca2+ channel. Pharmacological Research (2012) 65(2):239-46. (Impact factor: 658)
  31. Cheang WS, Wong WT, Tian XY, Yang Q, Lee HK, He GW, Yao X, Huang Y. Endothelial nitric oxide synthase enhancer reduces oxidative stress and restores endothelial function in db/db mice. Cardiovascular Research (2011) 92(2):267-75. (Impact factor: 10.787)
  32. Cheang WS, Wong WT, Shen B, Lau CW, Tian XY, Tsang SY, Yao X, Chen ZY, Huang Y. 4-Aminopyridine-sensitive K+ channels contributes to NaHS-induced membrane hyperpolarization and relaxation in the rat coronary artery. Vascular Pharmacology (2010) 53(3-4):94-8. (Impact factor: 5.773)

Book chapters

  1. Nagappan T, *Cheang WS (2020) Ginsenosides in Diets. In: Xiao J., Sarker S., Asakawa Y. (eds) Handbook of Dietary Phytochemicals. Springer, Singapore
  • Editorial Board Member, Journal of Clinical Cardiology and Cardiovascular Diagnosis (2021-present)
  • Editorial Board Member, Open Access Journal of Pharmaceutical Research (2019-present)
  • Editorial Board Member, Food Science and Nutrition Technology (2016-present)
  • Editorial Board Member, SM Vascular Medicine (2016-2017)