Email

ytwang@um.edu.mo

Yitao WANG 王一濤

Emeritus Professor, Institute of Chinese Medical Sciences

Director, The Chinese Medicine and the Translational Medicine R&D Center, Zhuhai UM Science & Technology Research Institute (ZUMRI)

Academic Qualifications

Postgraduate, Chongqing Medical University
BSc, Chengdu University of Chinese Medicine

Research Interests

  • Systematic quality evaluation of Chinese Medicine
  • Drug discovery and development
  • Medicinal administration

Prof. Wang was Director of Institute of Chinese Materia Medica, and Vice President of China Academy of Chinese Medical Sciences in 1996, where he became the Chief Scientist in 1999. He was appointed as Professor and Director for the CM Programme at Hong Kong University of Science and Technology (HKUST) in 2000-2002. In 2002, he was invited to join UM to initiate ICMS as the founding director, and he subsequently founded SKL-QRCM as the founding director. He was appointed as Chair Professor at UM in 2013.

Prof. Wang has devoted himself into the medicinal education and Chinese Medicine (CM) studies. He founded the first national key discipline in CM, the first national talents programme in CM. He was also the Chief Scientist for the first National Basic Research Program of China (973 Program) in TCM, and initiated and led the foundation of the first SKL in TCM in China.

He has supervised more than 100 PhD and MSc students, published 446 SCI papers with a total citation of 19298 times and h-index of 71，and edited 16 books in CM and has 16 patents. He became the National Council Special Allowance Expert in 1992, and won numerous awards including Macau Medal of Merit-Education (2011), National Science and Technology Progress Award (2016), Macao Science and Technology Awards-Special Award (2018), the 5th Cheung On Tak International Award for Outstanding Contribution to Chinese Medicine (2020), and eight other prestigious awards issued by Macao SAR governments and Ministries of China.

In 2020, Prof. Wang has been appointed as the Deputy Team Leader of CM Prescriptions Screening of the Joint Prevention and Control Panel of the State Council, and a member of the Coordination Group for Promotion of the Chinese Medicine Industry of the Macao SAR Government. He has also been a member of the Macao SAR Economic Development Committee, Science and Technology Committee and Medical Affairs Committee, as well as in several national committee including National Science and Technology Programmes, the State Science and Technology Awards, National Natural Science Foundation, and NMPA Centre for Drug Evaluation. He is also General Secretory for the International Society for Chinese Medicine, Chairman of International Society of Quality Research in Chinese Medicine, executive member of the Presidium of the World Federation of Chinese Medicine Societies, and Editor-in-Chief of a SCI journal “Chinese Medicine” (ranked the first in Impact Factor among all TCM journals in greater China region).

Book chapters / Monographs

  1. Advances in Chinese Medicinal Approach to Cancer. Beijing: People’s Medical Publishing House, 2012, ISBN 9787117162272, 7117162279. Chief Editor
  2. Chromatographic Analysis of Commonly Used Chinese Material Medica, Macao: University of Macau Press, 2009, ISBN 978-99937-970-6-7. Co-Chief Editor.
  3. Pharmacological Activity-Based Quality Control of Chinese Herbs, Nova Science Publishers, Inc, 2008, ISBN-10: 1-60456-823-2. Co-Chief Editor.
  4. Chinese Medical Sciences collection Series (A)–Progress in Medicinal Administration Research. Macao: University of Macau Press, 2005, ISBN 99937-26-50-8. Chief Editor.
  5. Chinese Medical Sciences collection Series (B)–Progress in Traditional Chinese Medical Research. Macao: University of Macau Press, 2005, ISBN 99937-26-51-6. Chief Editor.
  6. Chinese Medical Sciences collection Series (C) – Quality Evaluation for Chinese Medicine 1. Macao: University of Macau Press, 2005, ISBN 99937-26-52-4. Chief Editor.
  7. Chinese Medical Sciences collection Series (C) – Quality Evaluation for Chinese Medicine 2. Macao: University of Macau Press, 2005, ISBN 99937-26-53-2. Chief Editor.
  8. Chinese Medical Sciences collection Series (C) – Quality Evaluation for Chinese Medicine 3. Macao: University of Macau Press, 2005, ISBN 99937-26-54-0. Chief Editor.
  9. Chinese Medical Sciences collection Series (C) – Quality Evaluation for Chinese Medicine 4. Macao: University of Macau Press, 2005, ISBN 99937-26-55-9. Chief Editor.
  10. Chinese Medical Sciences collection Series (C) – Quality Evaluation for Chinese Medicine 5. Macao: University of Macau Press, 2005, ISBN 99937-26-56-7. Chief Editor.
  11. Chinese Medical Sciences collection Series (C) – Quality Evaluation for Chinese Medicine 6. Macao: University of Macau Press, 2005, ISBN 99937-26-57-5. Chief Editor.
  12. Chinese Terms in Chinese Medicine and Pharmacy. Beijing: Science Press, 2005, ISBN 7-03-015154-2, Associate Editor.
  13. Intellectual Property Protection of TCM. Beijing: China Press of TCM, 2003, ISBN 7-80-15641-89, Chief Editor.
  14. Drug Administration of European Union and Traditional Chinese Medicine. China International Culture Press Limited, 1999, Associate Editor.
  15. Traditional Chinese Medicine pharmacology and application. Beijing: People’s Medical Publishing House, 1997, ISBN 7-117-03057-7/R.3058, Associate Editor.
  16. New product development from Traditional Chinese Medicine. Beijing: People’s Medical Publishing House, 1997, ISBN 7-117-02640-5, Chief Editor.

International peer-reviewed journals （01/2010-2018/11）

  1. Xiong W, Zhao GD, Yin XQ, Gang LHK, Chu JMT, Wong GTC, Li HF, Yu H, Wang YT. Brij-grafted-chitosan copolymers with function of P-glycoprotein modulation: Synthesis, characterization and in vitro investigations. Carbohydrate Polymers. 2019; 204:89-96.
  2. Zhou FY, Wang AQ, Li D, Wang YT, Lin LG. Pinocembrin from Penthorum chinense Pursh suppresses hepatic stellate cells activation through a unified SIRT3-TGF-beta-Smad signaling pathway. Toxicology and Applied Pharmacology. 2018; 341:38-50.
  3. Zhong ZF, Yu HB, Wang SP, Wang YT, Cui L. Anti-cancer effects of Rhizoma Curcumae against doxorubicin-resistant breast cancer cells. Chinese Medicine. 2018; 13.
  4. Zhao QQ, Miriyala N, Su Y, Chen WJ, Gao XJ, Shao L, Yan R, Li HF, Yao XJ, Cao DS, Wang YT, Ouyang DF. Computer-Aided Formulation Design for a Highly Soluble Lutein-Cyclodextrin Multiple-Component Delivery System. Molecular Pharmaceutics. 2018; 15:1664-1673.
  5. Zhang LL, Feng ZL, Su MX, Jiang XM, Chen XP, Wang YT, Li A, Lin LG, Lu JJ. Downregulation of Cyclin B1 mediates nagilactone E-induced G2 phase cell cycle arrest in non-small cell lung cancer cells. European Journal of Pharmacology. 2018; 830:17-25.
  6. Zhang L, Dou XW, Zhang C, Ying GY, Liu CM, Luo JY, Li Q, Li P, Wang YT, Yang MH. Facile preparation of stable PEG-functionalized quantum dots with glycine-enhanced photoluminescence and their application for screening of aflatoxin B-1 in herbs. Sensors and Actuators B-Chemical. 2018; 261:188-195.
  7. Zhane JM, Fang XB, Li ZY, Chan HF, Lin ZX, Wang YT, Chen MW. Redox-sensitive micelles composed of disulfide-linked Pluronic-linoleic acid for enhanced anticancer efficiency of brusatol. International Journal of Nanomedicine. 2018; 13:939-956.
  8. Xiong W, Sang W, Linghu KG, Zhong ZF, Cheang WS, Li J, Hu YJ, Yu H, Wang YT. Dual-functional Brij-S20-modified nanocrystal formulation enhances the intestinal transport and oral bioavailability of berberine. International Journal of Nanomedicine. 2018; 13:3781-3793.
  9. Xia FB, Li A, Chai YS, Xiao X, Wan JB, Li P, Wang YT. UPLC/Q-TOFMS-Based Metabolomics Approach to Reveal the Protective Role of Other Herbs in An-Gong-Niu-Huang Wan Against the Hepatorenal Toxicity of Cinnabar and Realgar. Frontiers in Pharmacology. 2018; 9.
  10. Wei JC, Wei B, Yang W, He CW, Su HX, Wan JB, Li P, Wang YT. Trace determination of carbamate pesticides in medicinal plants by a fluorescent technique. Food and Chemical Toxicology. 2018; 119:430-437.
  11. Wang SP, Xu YQ, Li CY, Tao HX, Wang AQ, Sun CY, Zhong ZF, Wu X, Li P, Wang YT. Gambogic acid sensitizes breast cancer cells to TRAIL-induced apoptosis by promoting the crosstalk of extrinsic and intrinsic apoptotic signalings. Food and Chemical Toxicology. 2018; 119:334-341.
  12. Wang AQ, Wang SP, Zhou FY, Li P, Wang YT, Gan LS, Lin LG. Physalin B induces cell cycle arrest and triggers apoptosis in breast cancer cells through modulating p53-dependent apoptotic pathway. Biomedicine & Pharmacotherapy. 2018; 101:334-341.
  13. Wang AQ, Li D, Wang SP, Zhou FY, Li P, Wang YT, Lin LG. gamma-Mangostin, a xanthone from mangosteen, attenuates oxidative injury in liver via NRF2 and SIRT1 induction. Journal of Functional Foods. 2018; 40:544-553.
  14. Tao HX, Xiong W, Zhao GD, Peng Y, Zhong ZF, Xu L, Duan R, Tsim KWK, Yu H, Wang YT. Discrimination of three Siegesbeckiae Herba species using UPLC-QTOF/MS-based metabolomics approach. Food and Chemical Toxicology. 2018; 119:400-406.
  15. Song QQ, Liu WJ, Chen XJ, Li J, Li P, Yang FQ, Wang YT, Song YL, Tu PF. Serially coupled reversed phase-hydrophilic interaction liquid chromatography-tailored multiple reaction monitoring, a fit-for-purpose tool for large-scale targeted metabolomics of medicinal bile. Analytica Chimica Acta. 2018; 1037:119-129.
  16. Shen SN, Liao QW, Huang L, Li D, Zhang QW, Wang YT, Lee SMY, Lin LG. Water soluble fraction from ethanolic extract of Clausena lansium seeds alleviates obesity and insulin resistance, and changes the composition of gut microbiota in high-fat diet-fed mice. Journal of Functional Foods. 2018; 47:192-199.
  17. Sang W, Zhong ZF, Linghu KG, Xiong W, Tse AKW, Cheang WS, Yu H, Wang YT. Siegesbeckia pubescens Makino inhibits Pam(3)CSK(4)-induced inflammation in RAW 264.7 macrophages through suppressing TLR1/TLR2-mediated NF-kappa B activation. Chinese Medicine. 2018; 13.
  18. Qu LP, Zou WJ, Wang YT, Wang M. European regulation model for herbal medicine: The assessment of the EU monograph and the safety and efficacy evaluation in marketing authorization or registration in Member States. Phytomedicine. 2018; 42:219-225.
  19. Ma XW, Hu YC, Li X, Zheng XT, Wang YT, Zhang JM, Fu CM, Geng FN. Periplaneta americana Ameliorates Dextran Sulfate Sodium-Induced Ulcerative Colitis in Rats by Keap1/Nrf-2 Activation, Intestinal Barrier Function, and Gut Microbiota Regulation. Frontiers in Pharmacology. 2018; 9.
  20. Luo WW, Zhao WW, Lu JJ, Wang YT, Chen XP. Cucurbitacin B suppresses metastasis mediated by reactive oxygen species (ROS) via focal adhesion kinase (FAK) in breast cancer MDA-MB-231 cells. Chinese Journal of Natural Medicines. 2018; 16:10-19.
  21. Luo W, Liu X, Sun W, Lu JJ, Wang YT, Chen XP. Toosendanin, a natural product, inhibited TGF-1-induced epithelial-mesenchymal transition through ERK/Snail pathway. Phytotherapy Research. 2018; 32:2009-2020.
  22. Liu Y, Song QQ, Liu WJ, Li P, Li J, Zhao YF, Zhang L, Tu PF, Wang YT, Song YL. Authentic compound-free strategy for simultaneous determination of primary coumarins in Peucedani Radix using offline high performance liquid chromatography-nuclear magnetic resonance spectroscopy-tandem mass spectrometry. Acta Pharmaceutica Sinica B. 2018; 8:645-654.
  23. Liu WJ, Song QQ, Yan Y, Liu Y, Li P, Wang YT, Tu PF, Song YL, Li J. Integrated approach for confidence-enhanced quantitative analysis of herbal medicines, Cistanche salsa as a case. Journal of Chromatography A. 2018; 1561:56-66.
  24. Liu JX, Shen SN, Tong Q, Wang YT, Lin LG. Honokiol protects hepatocytes from oxidative injury through mitochondrial deacetylase SIRT3. European Journal of Pharmacology. 2018; 834:176-187.
  25. Li F, Li XM, Sheng DK, Chen SR, Nie X, Liu ZY, Wang DC, Zhao Q, Wang YT, Wang Y, Zhou GC. Discovery and preliminary SAR of 14-aryloxy-andrographolide derivatives as antibacterial agents with immunosuppressant activity. Rsc Advances. 2018; 8:9440-9456.
  26. Li A, Zhang JY, Xiao X, Wang SS, Wan JB, Chai YS, Li P, Wang YT. Hepatorenal protective effects of medicinal herbs in An-Gong-Niu-Huang Wan (AGNH) against cinnabar- and realgar-induced oxidative stress and inflammatory damage in mice. Food and Chemical Toxicology. 2018; 119:445-456.
  27. Chen SR, Li F, Ding MY, Wang DC, Zhao Q, Wang YT, Zhou GC, Wang Y. Andrographolide derivative as STAT3 inhibitor that protects acute liver damage in mice. Bioorganic & Medicinal Chemistry. 2018; 26:5053-5061.
  28. Chen SR, Dai Y, Zhao J, Lin LG, Wang YT, Wang Y. A Mechanistic Overview of Triptolide and Celastrol, Natural Products from Tripterygium wilfordii Hook F. Frontiers in Pharmacology. 2018; 9.
  29. Cao JL, Wang SS, Hu H, He CW, Wan JB, Su HX, Wang YT, Li P. Online comprehensive two-dimensional hydrophilic interaction chromatography x reversed-phase liquid chromatography coupled with hybrid linear ion trap Orbitrap mass spectrometry for the analysis of phenolic acids in Salvia miltiorrhiza. Journal of Chromatography A. 2018; 1536:216-227.
  30. Bao JL, Ding RB, Jia XJ, Liang YE, Liu F, Wang K, Zhang C, Li P, Wang YT, Wan JB, He CW. Fast identification of anticancer constituents in Forsythiae Fructus based on metabolomics approaches. Journal of Pharmaceutical and Biomedical Analysis. 2018; 154:312-320.
  31. Zhong ZF, Yu HB, Wang CM, Qiang WA, Wang SP, Zhang JM, Yu H, Cui L, Wu T, Li DQ, Wang YT. Furanodiene Induces Extrinsic and Intrinsic Apoptosis in Doxorubicin-Resistant MCF-7 Breast Cancer Cells via NF-kappa B-Independent Mechanism. Frontiers in Pharmacology. 2017; 8.
  32. Zhong ZF, Yu HB, Wang CM, Qiang WA, Wang SP, Zhang JM, Yu H, Cui L, Wu T, Li DQ, Wang YT. Furanodiene Induces Extrinsic and Intrinsic Apoptosis in Doxorubicin-Resistant MCF-7 Breast Cancer Cells via NF-kappa B-Independent Mechanism (vol 8, 648, 2017). Frontiers in Pharmacology. 2017; 8.
  33. Zhong ZF, Tan W, Tian K, Yu H, Qiang WA, Wang YT. Combined effects of furanodiene and doxorubicin on the migration and invasion of MDA-MB-231 breast cancer cells in vitro. Oncology Reports. 2017; 37:2016-2024.
  34. Zhao QQ, Zhang WX, Wang RM, Wang YT, Ouyang DF. Research Advances in Molecular Modeling in Cyclodextrins. Current Pharmaceutical Design. 2017; 23:522-531.
  35. Zhang WX, Zhao QQ, Deng JL, Hu YJ, Wang YT, Ouyang DF. Big data analysis of global advances in pharmaceutics and drug delivery 1980-2014. Drug Discovery Today. 2017; 22:1201-1208.
  36. Zhang WX, Wang YT, Ouyang DF. Diversity of Pharmacy Faculty Members between UK and US. Indian Journal of Pharmaceutical Education and Research. 2017; 51:20-24.
  37. Zhang QR, Yu H, Qi J, Tang DS, Chen XJ, Wan JB, Li P, Hu H, Wang YT, Hu YJ. Natural formulas and the nature of formulas: Exploring potential therapeutic targets based on traditional Chinese herbal formulas. Plos One. 2017; 12.
  38. Zhang JM, Zheng YF, Xie X, Wang L, Su ZR, Wang YT, Leong KW, Chen MW. Cleavable Multifunctional Targeting Mixed Micelles with Sequential pH-Triggered TAT Peptide Activation for Improved Antihepatocellular Carcinoma Efficacy. Molecular Pharmaceutics. 2017; 14:3644-3659.
  39. Zhang JM, Wang L, Chan HF, Xie W, Chen S, He CW, Wang YT, Chen MW. Co-delivery of paclitaxel and tetrandrine via iRGD peptide conjugated lipid-polymer hybrid nanoparticles overcome multidrug resistance in cancer cells. Scientific Reports. 2017; 7.
  40. Zhang JM, Li JJ, Shi Z, Yang Y, Xie X, Lee SM, Wang YT, Leong KW, Chen MW. pH-sensitive polymeric nanoparticles for co-delivery of doxorubicin and curcumin to treat cancer via enhanced pro-apoptotic and anti-angiogenic activities. Acta Biomaterialia. 2017; 58:349-364.
  41. Yao DN, Xi XY, Huang YK, Hu H, Hu YJ, Wang YT, Yao WB. A national survey of clinical pharmacy services in county hospitals in China. Plos One. 2017; 12.
  42. Yan Y, Song QQ, Chen XJ, Li J, Li P, Wang YT, Liu TX, Song YL, Tu PF. Simultaneous determination of components with wide polarity and content ranges in Cistanche tubulosa using serially coupled reverse phase-hydrophilic interaction chromatography-tandem mass spectrometry. Journal of Chromatography A. 2017; 1501:39-50.
  43. Xu XH, Zhang LL, Wu GS, Chen X, Li T, Chen XP, Wang YT, Lu JJ. Solasodine Induces Apoptosis, Affects Autophagy, and Attenuates Metastasis in Ovarian Cancer Cells. Planta Medica. 2017; 83:254-260.
  44. Xu XH, Liu QY, Li T, Liu JL, Chen X, Huang L, Qiang WA, Chen XP, Wang YT, Lin LG, Lu JJ. Garcinone E induces apoptosis and inhibits migration and invasion in ovarian cancer cells. Scientific Reports. 2017; 7.
  45. Wu X, Wang SP, Li MX, Wang AQ, Zhou YY, Li P, Wang YT. Nanocarriers for TRAIL delivery: driving TRAIL back on track for cancer therapy. Nanoscale. 2017; 9:13879-13904.
  46. Wu WJ, Yan R, Li T, Li YP, Zhou RN, Wang YT. Pharmacokinetic alterations of rhubarb anthraquinones in experimental colitis induced by dextran sulfate sodium in the rat. Journal of Ethnopharmacology. 2017; 198:600-607.
  47. Wu MY, Wang SF, Cai CZ, Tan JQ, Li M, Lu JJ, Chen XP, Wang YT, Zheng W, Lu JH. Natural autophagy blockers, dauricine (DAC) and daurisoline (DAS), sensitize cancer cells to camptothecin-induced toxicity. Oncotarget. 2017; 8:77673-77684.
  48. Wei JC, Cao JL, Hu H, Yang Q, Yang FQ, Wan JB, Su HX, He CW, Li P, Wang YT. Sensitive and Selective Detection of Oxo-Form Organophosphorus Pesticides Based on CdSe/ZnS Quantum Dots. Molecules. 2017; 22.
  49. Wang YF, Xu YL, Tang ZH, Li T, Zhang LL, Chen XP, Lu JH, Leung CH, Ma DL, Qiang WA, Wang YT, Lu JJ. Baicalein Induces Beclin 1-and Extracellular Signal-Regulated Kinase-Dependent Autophagy in Ovarian Cancer Cells. American Journal of Chinese Medicine. 2017; 45:123-136.
  50. Wang YF, Tang ZH, Li T, Xu XH, Chen XP, Wang Y, Wang YT, Lu JJ. Baicalein protects tert-butyl hydroperoxide-induced hepatotoxicity dependent of reactive oxygen species removal. Molecular Medicine Reports. 2017; 16:8392-8398.
  51. Wang SP, Wang AQ, Shao M, Lin LG, Li P, Wang YT. Schisandrin B reverses doxorubicin resistance through inhibiting P-glycoprotein and promoting proteasome-mediated degradation of survivin. Scientific Reports. 2017; 7.
  52. Wang SP, Shao M, Zhong ZF, Wang AQ, Cao JL, Lu YC, Wang YT, Zhang JM. Co-delivery of gambogic acid and TRAIL plasmid by hyaluronic acid grafted PEI-PLGA nanoparticles for the treatment of triple negative breast cancer. Drug Delivery. 2017; 24:1791-1800.
  53. Wang CM, Lei CK, Wang RB, Xiao JB, Wang YT. Ten years of exploration, a new journey to start: advancing Chinese Medicine to the next level. Chinese Medicine. 2017; 12.
  54. Tang ZH, Zhang LL, Chen X, Chen XP, Wang YT, Lu JJ. The effects and mechanisms of two main constituents from Glycyrrhiza uralensis Fisch-induced autophagy in non-small cell lung cancer. Biochemical Pharmacology. 2017; 139:123-123.
  55. Tan W, Zhong ZF, Wang SP, Liu H, Yu H, Tan R, Hu XD, Pan TR, Wang YT. The Typical Metabolic Modifiers Conferring Improvement in Cancer Resistance. Current Medicinal Chemistry. 2017; 24:3698-3710.
  56. Sun W, Wang S, Zhao WW, Wu CH, Guo SH, Gao HW, Tao HX, Lu JJ, Wang YT, Chen XP. Chemical constituents and biological research on plants in the genus Curcuma. Critical Reviews in Food Science and Nutrition. 2017; 57:1451-1523.
  57. Song YL, Song QQ, Liu Y, Li J, Wan JB, Wang YT, Jiang Y, Tu PF. Integrated work-flow for quantitative metabolome profiling of plants, Peucedani Radix as a case. Analytica Chimica Acta. 2017; 953:40-47.
  58. Song QQ, Zhao YF, Chen XJ, Li J, Li P, Jiang Y, Wang YT, Song YL, Tu PF. New instrumentation for large-scale quantitative analysis of components spanning a wide polarity range by column-switching hydrophilic interaction chromatography-turbulent flow chromatography-reversed phase liquid chromatography-tandem mass spectrometry. Rsc Advances. 2017; 7:31838-31849.
  59. Song QQ, Liu WJ, Yan Y, Li P, Li J, Tu PF, Wang YT, Song YL. Polarity-extended quantitative analysis of bear bile and its analogues using serially coupled reversed phase-hydrophilic interaction liquid chromatography-tailored multiple reaction monitoring. Rsc Advances. 2017; 7:52822-52831.
  60. Niu YM, Li Q, Xie RY, Liu S, Wang RB, Xing PF, Shi YC, Wang YT, Dong L, Wang CM. Modulating the phenotype of host macrophages to enhance osteogenesis in MSC-laden hydrogels: Design of a glucomannan coating material. Biomaterials. 2017; 139:39-55.
  61. Nie X, Chen SR, Wang K, Peng YR, Wang YT, Wang DC, Wang Y, Zhou GC. Attenuation of Innate Immunity by Andrographolide Derivatives Through NF-kappa B Signaling Pathway. Scientific Reports. 2017; 7.
  62. Ni JY, Zhao JR, Ung COL, Hu YJ, Hu H, Wang YT. Obstacles and opportunities in Chinese pharmaceutical innovation. Globalization and Health. 2017; 13.
  63. Liu LJ, Wang WH, Zhong ZF, Lin S, Lu LH, Wang YT, Ma DL, Leung CH. Inhibition of TLR1/2 dimerization by enantiomers of metal complexes (vol 52, pg 12278, 2016). Chemical Communications. 2017; 53:1325-1325.
  64. Li YX, Gong XH, Liu MC, Peng C, Li P, Wang YT. A New Strategy for Quality Evaluation and Identification of Representative Chemical Components in Polygonum multiflorum Thunb. Evidence-Based Complementary and Alternative Medicine. 2017.
  65. Li YX, Gong XH, Liu MC, Peng C, Li P, Wang YT. Investigation of Liver Injury of Polygonum multiflorum Thunb. in Rats by Metabolomics and Traditional Approaches. Frontiers in Pharmacology. 2017; 8.
  66. Li Q, Niu YM, Diao HJ, Wang LT, Chen XP, Wang YT, Dong L, Wang CM. In situ sequestration of endogenous PDGF-BB with an ECM-mimetic sponge for accelerated wound healing. Biomaterials. 2017; 148:54-68.
  67. Li A, Zhang XX, Shu M, Wu MJ, Wang J, Zhang JY, Wang R, Li P, Wang YT. Arctigenin suppresses renal interstitial fibrosis in a rat model of obstructive nephropathy. Phytomedicine. 2017; 30:28-41.
  68. Li A, Zhang JY, Zhang XX, Wang J, Wang SS, Xiao X, Wang R, Li P, Wang YT. Angiotensin II induces connective tissue growth factor expression in human hepatic stellate cells by a transforming growth factor beta-independent mechanism. Scientific Reports. 2017; 7.
  69. Jing WH, Gao XJ, Han BL, Wei B, Hu N, Li S, Yan R, Wang YT. Mori Cortex regulates P-glycoprotein in Caco-2 cells and colons from rats with experimental colitis via direct and gut microbiota-mediated mechanisms. Rsc Advances. 2017; 7:2594-2605.
  70. Huang LJ, Chen SR, Yuan CM, Gu W, Guo BJ, Wang YT, Wang Y, Hao XJ. C-21-steroidal pregnane sapogenins and their derivatives as anti-inflammatory agents. Bioorganic & Medicinal Chemistry. 2017; 25:3512-3524.
  71. Huang L, Feng ZL, Wang YT, Lin LG. Anticancer carbazole alkaloids and coumarins from Clausena plants: A review. Chinese Journal of Natural Medicines. 2017; 15:881-888.
  72. Guo BJ, Bian ZX, Qiu HC, Wang YT, Wang Y. Biological and clinical implications of herbal medicine and natural products for the treatment of inflammatory bowel disease. Annals of the New York Academy of Sciences. 2017; 1401:37-48.
  73. Feng ZL, Li D, Liu QY, Liu JX, Huang L, Zhang QW, Wang YT, Lin LG. Anti-inflammatory abietane diterpenoids from the seeds of Podocarpus nagi. Phytochemistry Letters. 2017; 21:260-263.
  74. Feng HT, Zhao WW, Lu JJ, Wang YT, Chen XP. Hypaconitine inhibits TGF-beta 1-induced epithelial-mesenchymal transition and suppresses adhesion, migration, and invasion of lung cancer A549 cells. Chinese Journal of Natural Medicines. 2017; 15:427-435.
  75. Feng HT, Lu JJ, Wang YT, Pei LX, Chen XP. Osthole inhibited TGF beta-induced epithelial-mesenchymal transition (EMT) by suppressing NF-kappa B mediated Snail activation in lung cancer A549 cells. Cell Adhesion & Migration. 2017; 11:464-475.
  76. Chen X, Wu QS, Meng FC, Tang ZH, Chen XP, Lin LG, Chen P, Qiang WA, Wang YT, Zhang QW, Lu JJ. Chikusetsusaponin IVa methyl ester induces G1 cell cycle arrest, triggers apoptosis and inhibits migration and invasion in ovarian cancer cells (vol 23, pg 1555, 2016). Phytomedicine. 2017; 29:E1-E1.
  77. Chen FQ, Zhang JM, Fang XF, Yu H, Liu YL, Li H, Wang YT, Chen MW. Reversal of paclitaxel resistance in human ovarian cancer cells with redox-responsive micelles consisting of alpha-tocopheryl succinate-based polyphosphoester copolymers. Acta Pharmacologica Sinica. 2017; 38:859-873.
  78. Cao H, Wang YT, Xiao JB. Dietary Polyphenols and Type 2 Diabetes: Human Study and Clinical Trial. Free Radical Biology and Medicine. 2017; 112:158-158.
  79. Cao H, Chai TT, Wang X, Morais-Braga MFB, Yang JH, Wong FC, Wang RB, Yao HK, Cao JG, Cornara L, Burlando B, Wang YT, Xiao JB, Coutinho HDM. Phytochemicals from fern species: potential for medicine applications. Phytochemistry Reviews. 2017; 16:379-440.
  80. Bao JL, Ding RB, Liang YE, Liu F, Wang K, Jia XJ, Zhang C, Chen MW, Li P, Su HX, Wan JB, Wang YT, He CW. Differences in Chemical Component and Anticancer Activity of Green and Ripe Forsythiae Fructus. American Journal of Chinese Medicine. 2017; 45:1513-1536.
  81. Zou LD, Chen FQ, Bao JL, Wang SP, Wang L, Chen MW, He CW, Wang YT. Preparation, characterization, and anticancer efficacy of evodiamine-loaded PLGA nanoparticles. Drug Delivery. 2016; 23:908-916.
  82. Zhong ZF, Tan W, Qiang WW, Scofield VL, Tian K, Wang CM, Qiang WA, Wang YT. Furanodiene alters mitochondrial function in doxorubicin-resistant MCF-7 human breast cancer cells in an AMPK-dependent manner. Molecular Biosystems. 2016; 12:1626-1637.
  83. Zhong ZF, Qiang WW, Tan W, Zhang HT, Wang SP, Wang CM, Qiang WN, Wang YT. Chinese Herbs Interfering with Cancer Reprogramming Metabolism. Evidence-Based Complementary and Alternative Medicine. 2016.
  84. Zhong ZF, Qiang WA, Wang CM, Tan W, Wang YT. Furanodiene enhances the anti-cancer effects of doxorubicin on ER alpha-negative breast cancer cells in vitro. European Journal of Pharmacology. 2016; 774:10-19.
  85. Zhang M, Kong XJ, Zheng J, Wan JB, Wang YT, Hu YJ, Shao R. Research and development of antibiotics: insights from patents and citation network. Expert Opinion on Therapeutic Patents. 2016; 26:617-627.
  86. Zhang LL, Xu YL, Tang ZH, Xu XH, Chen X, Li T, Ding CY, Huang MQ, Chen XP, Wang YT, Yuan XF, Lu JJ. Effects of alisol B 23-acetate on ovarian cancer cells: G1 phase cell cycle arrest, apoptosis, migration and invasion inhibition. Phytomedicine. 2016; 23:800-809.
  87. Zhang LL, Tian K, Tang ZH, Chen XJ, Bian ZX, Wang YT, Lu JJ. Phytochemistry and Pharmacology of Carthamus tinctorius L. American Journal of Chinese Medicine. 2016; 44:197-226.
  88. Zhang C, Jia XJ, Bao JL, Chen SH, Wang K, Zhang YL, Li P, Wan JB, Su HX, Wang YT, Mei ZN, He CW. Polyphyllin VII induces apoptosis in HepG2 cells through ROS-mediated mitochondrial dysfunction and MAPK pathways. Bmc Complementary and Alternative Medicine. 2016; 16.
  89. Yang BR, Hong SJ, Lee SMY, Cong WH, Wan JB, Zhang ZR, Zhang QW, Zhang Y, Wang YT, Lin ZX. Pro-angiogenic activity of notoginsenoside R1 in human umbilical vein endothelial cells in vitro and in a chemical-induced blood vessel loss model of zebrafish in vivo. Chinese Journal of Integrative Medicine. 2016; 22:420-429.
  90. Xu XH, Li T, Fong CMV, Chen XP, Chen XJ, Wang YT, Huang MQ, Lu JJ. Saponins from Chinese Medicines as Anticancer Agents. Molecules. 2016; 21.
  91. Xu HB, Song JY, Luo HM, Zhang YJ, Li QS, Zhu YJ, Xu J, Li Y, Song C, Wang B, Sun W, Shen GA, Zhang X, Qian J, Ji AJ, Xu ZC, Luo X, He L, Li CY, Sun C, Yan HX, Cui GH, Li XW, Li XE, Wei JH, Liu JY, Wang YT, Hayward A, Nelson D, Ning Z, Peters RJ, Qi XQ, Chen SL. Analysis of the Genome Sequence of the Medicinal Plant Salvia miltiorrhiza. Molecular Plant. 2016; 9:949-952.
  92. Wang SP, Zhang JM, Wang YT, Chen MW. Hyaluronic acid-coated PEI-PLGA nanoparticles mediated co-delivery of doxorubicin and miR-542-3p for triple negative breast cancer therapy. Nanomedicine-Nanotechnology Biology and Medicine. 2016; 12:411-420.
  93. Wang SP, Xu YQ, Chan HF, Kim HW, Wang YT, Leong KW, Chen MW. Nanoparticle-mediated inhibition of survivin to overcome drug resistance in cancer therapy. Journal of Controlled Release. 2016; 240:454-464.
  94. Wang CZ, Yu CH, Wen XD, Chen LN, Zhang CF, Calway T, Qiu YP, Wang YW, Zhang ZY, Anderson S, Wang YT, Jia W, Yuan CS. American Ginseng Attenuates Colitis-Associated Colon Carcinogenesis in Mice: Impact on Gut Microbiota and Metabolomics. Cancer Prevention Research. 2016; 9:803-811.
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  96. Ung COL, Chao CK, Hu YJ, Zhao J, Li P, Wang YT, Hu H. Community pharmacists’ understanding, attitudes, practice and perceived barriers related to providing pharmaceutical care: a questionnaire-based survey in Macao. Tropical Journal of Pharmaceutical Research. 2016; 15:847-854.
  97. Tang ZH, Chen X, Wang ZY, Chai K, Wang YF, Xu XH, Wang XW, Lu JH, Wang YT, Chen XP, Lu JJ. Induction of C/EBP homologous protein-mediated apoptosis and autophagy by licochalcone A in non-small cell lung cancer cells. Scientific Reports. 2016; 6.
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  99. Ni JY, Wan JB, Kong XJ, Cai Y, Yang FQ, Wang YT, Hu YJ. Pharmaceutical Technology Licensing: An Analysis in the Field of Cardiovascular Disease. Journal of Pharmaceutical Innovation. 2016; 11:34-45.
  100. Ma GX, Luo WW, Lu JJ, Ma DL, Leung CH, Wang YT, Chen XP. Cucurbitacin E induces caspase-dependent apoptosis and protective autophagy mediated by ROS in lung cancer cells. Chemico-Biological Interactions. 2016; 253:1-9.
  101. Liu LJ, Wang WH, Zhong ZF, Lin S, Lu LH, Wang YT, Ma DL, Leung CH. Inhibition of TLR1/2 dimerization by enantiomers of metal complexes. Chemical Communications. 2016; 52:12278-12281.
  102. Lin ZQ, Xu SX, Gao W, Hu HX, Chen MW, Wang YT, He B, Dai WB, Zhang H, Wang XQ, Dong AJ, Yin YX, Zhang Q. A comparative investigation between paclitaxel nanoparticle- and nanocrystal-loaded thermosensitive PECT hydrogels for peri-tumoural administration. Nanoscale. 2016; 8:18782-18791.
  103. Lin S, Yang C, Mao ZF, He BY, Wang YT, Leung CH, Ma DL. A G-pentaplex-based assay for Cs+ ions in aqueous solution using a luminescent Ir(III) complex. Biosensors & Bioelectronics. 2016; 77:609-612.
  104. Li SK, Wyman IW, Wang CM, Wang YT, Macartney DH, Wang RB. Inhibition of C(2)-H Activity on Alkylated Imidazolium Monocations and Dications upon Inclusion by Cucurbit 7 uril. Journal of Organic Chemistry. 2016; 81:9494-9498.
  105. Li Q, Guo GW, Meng FC, Wang HH, Niu YM, Zhang QW, Zhang JF, Wang YT, Dong L, Wang CM. A Naturally Derived, Growth Factor-Binding Polysaccharide for Therapeutic Angiogenesis. Acs Macro Letters. 2016; 5:617-621.
  106. Klionsky DJ, Abdelmohsen K, Abe A, Abedin MJ, Abeliovich H, Arozena AA, Adachi H, Adams CM, Adams PD, Adeli K, Adhihetty PJ, Adler SG, Wang YT, Zorzano A, Zughaier SM, et al. Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy. 2016; 12:1-222.
  107. Kang TS, Mao ZF, Ng CT, Wang MD, Wang WH, Wang CM, Lee SMY, Wang YT, Leung CH, Ma DL. Identification of an Iridium(III)-Based Inhibitor of Tumor Necrosis Factor-alpha. Journal of Medicinal Chemistry. 2016; 59:4026-4031.
  108. Guo SH, Luo WW, Liu LJ, Pang XC, Zhu H, Liu AL, Lu JJ, Ma DL, Leung CH, Wang YT, Chen XP. Isocryptotanshinone, a STAT3 inhibitor, induces apoptosis and pro-death autophagy in A549 lung cancer cells. Journal of Drug Targeting. 2016; 24:934-942.
  109. Chen XJ, Qiu JF, Wang YT, Wan JB. Discrimination of Three Panax Species Based on Differences in Volatile Organic Compounds Using a Static Headspace GC-MS-Based Metabolomics Approach. American Journal of Chinese Medicine. 2016; 44:663-676.
  110. Chen X, Wu QS, Meng FC, Tang ZH, Chen XP, Lin LG, Chen P, Qiang WA, Wang YT, Zhang QW, Lu JJ. Chikusetsusaponin IVa methyl ester induces G1 cell cycle arrest, triggers apoptosis and inhibits migration and invasion in ovarian cancer cells. Phytomedicine. 2016; 23:1555-1565.
  111. Chen SR, Wang AQ, Lin LG, Qiu HC, Wang YT, Wang Y. In Vitro Study on Anti-Hepatitis C Virus Activity of Spatholobus suberectus Dunn. Molecules. 2016; 21.
  112. Chen SR, Qiu HC, Hu Y, Wang Y, Wang YT. Herbal Medicine Offered as an Initiative Therapeutic Option for the Management of Hepatocellular Carcinoma. Phytotherapy Research. 2016; 30:863-877.
  113. Chen MH, Chen XJ, Wang M, Lin LG, Wang YT. Ophiopogon japonicus-A phytochemical, ethnomedicinal and pharmacological review. Journal of Ethnopharmacology. 2016; 181:193-213.
  114. Chen FQ, Zhang JM, He Y, Fang XF, Wang YT, Chen MW. Glycyrrhetinic acid-decorated and reduction-sensitive micelles to enhance the bioavailability and anti-hepatocellular carcinoma efficacy of tanshinone IIA. Biomaterials Science. 2016; 4:167-182.
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  116. Bao JL, Liu F, Zhang C, Wang K, Jia XJ, Wang XT, Chen MW, Li P, Su HX, Wang YT, Wan JB, He CW. Anti-melanoma activity of Forsythiae Fructus aqueous extract in mice involves regulation of glycerophospholipid metabolisms by UPLC/Q-TOF MS-based metabolomics study. Scientific Reports. 2016; 6.
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  118. Zhu YJ, Xu J, Sun C, Zhou SG, Xu HB, Nelson DR, Qian J, Song JY, Luo HM, Xiang L, Li Y, Xu ZC, Ji AJ, Wang LZ, Lu SF, Hayward A, Sun W, Li XW, Schwartz DC, Wang YT, Chen SL. Chromosome-level genome map provides insights into diverse defense mechanisms in the medicinal fungus Ganoderma sinense. Scientific Reports. 2015; 5.
  119. Zhong ZF, Tan W, Wang SP, Qiang WA, Wang YT. Anti-proliferative activity and cell cycle arrest induced by evodiamine on paclitaxel-sensitive and -resistant human ovarian cancer cells. Scientific Reports. 2015; 5.
  120. Zhong ZF, Liu LJ, Dong ZQ, Lu LH, Wang MD, Leung CH, Ma DL, Wang YT. Structure-based discovery of an immunomodulatory inhibitor of TLR1-TLR2 heterodimerization from a natural product-like database. Chemical Communications. 2015; 51:11178-11181.
  121. Zhang YL, Bao JL, Wang K, Jia XJ, Zhang C, Huang BR, Chen MW, Wan JB, Su HX, Wang YT, He CW. Pulsatilla Saponin D Inhibits Autophagic Flux and Synergistically Enhances the Anticancer Activity of Chemotherapeutic Agents Against HeLa Cells. American Journal of Chinese Medicine. 2015; 43:1657-1670.
  122. Zhang MY, Lu JJ, Wang L, Gao ZC, Hu H, Ung COL, Wang YT. Development of Monoclonal Antibodies in China: Overview and Prospects. Biomed Research International. 2015.
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  124. Zhang JM, Zhang M, Ji J, Fang XF, Pan X, Wang YT, Wu CB, Chen MW. Glycyrrhetinic Acid-Mediated Polymeric Drug Delivery Targeting the Acidic Microenvironment of Hepatocellular Carcinoma. Pharmaceutical Research. 2015; 32:3376-3390.
  125. Zhang JM, Chen RIE, Fang XF, Chen FQ, Wang YT, Chen MW. Nucleolin targeting AS1411 aptamer modified pH-sensitive micelles for enhanced delivery and antitumor efficacy of paclitaxel. Nano Research. 2015; 8:201-218.
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  127. Zhang C, Chen SH, Bao JL, Zhang YL, Huang BR, Jia XJ, Chen MW, Wan JB, Su HX, Wang YT, He CW. Low Doses of Camptothecin Induced Hormetic and Neuroprotective Effects in PC12 Cells. Dose-Response. 2015; 13.
  128. Yu XW, Hu H, Chen XP, Hu YJ, Wang YT. Technology Road Mapping for Innovation Pathways of Fibrates: A Cross-Database Patent Review. Tropical Journal of Pharmaceutical Research. 2015; 14:1459-1467.
  129. Xu YQ, Sun ZQ, Wang YT, Xiao F, Chen MW. Function of Nogo-A/Nogo-A Receptor in Alzheimer’s Disease. Cns Neuroscience & Therapeutics. 2015; 21:479-485.
  130. Wang YF, Li T, Tang ZH, Chang LL, Zhu H, Chen XP, Wang YT, Lu JJ. Baicalein Triggers Autophagy and Inhibits the Protein Kinase B/Mammalian Target of Rapamycin Pathway in Hepatocellular Carcinoma HepG2 Cells. Phytotherapy Research. 2015; 29:674-679.
  131. Wang Y, Liu JJ, Li Q, Wang YT, Wang CM. Two natural glucomannan polymers, from Konjac and Bletilla, as bioactive materials for pharmaceutical applications. Biotechnology Letters. 2015; 37:1-8.
  132. Wang SP, Yang Y, Wang YT, Chen MW. Gambogic acid-loaded pH-sensitive mixed micelles for overcoming breast cancer resistance. International Journal of Pharmaceutics. 2015; 495:840-848.
  133. Wang SP, Wang L, Chen MW, Wang YT. Gambogic acid sensitizes resistant breast cancer cells to doxorubicin through inhibiting P-glycoprotein and suppressing survivin expression. Chemico-Biological Interactions. 2015; 235:76-84.
  134. Wang SP, Qiu JG, Shi Z, Wang YT, Chen MW. Nanoscale drug delivery for taxanes based on the mechanism of multidrug resistance of cancer. Biotechnology Advances. 2015; 33:224-241.
  135. Wang SP, Chen R, Morott J, Repka MA, Wang YT, Chen MW. mPEG-b-PCL/TPGS mixed micelles for delivery of resveratrol in overcoming resistant breast cancer. Expert Opinion on Drug Delivery. 2015; 12:361-373.
  136. Wang RM, Zhou H, Siu SWI, Gan Y, Wang YT, Ouyang DF. Comparison of Three Molecular Simulation Approaches for Cyclodextrin-Ibuprofen Complexation. Journal of Nanomaterials. 2015.
  137. Wang DD, Jiang Y, Wu K, Wang S, Wang YT. Evaluation of antitumor property of extracts and steroidal alkaloids from the cultivated Bulbus Fritillariae ussuriensis and preliminary investigation of its mechanism of action. Bmc Complementary and Alternative Medicine. 2015; 15.
  138. Wang AQ, Liu QY, Ye Y, Wang YT, Lin LG. Identification of hepatoprotective xanthones from the pericarps of Garcinia mangostana, guided with tert-butyl hydroperoxide induced oxidative injury in HL-7702 cells. Food & Function. 2015; 6:3013-3021.
  139. Wang AQ, Lin LG, Wang YT. Traditional Chinese Herbal Medicine Penthorum chinense Pursh: A Phytochemical and Pharmacological Review. American Journal of Chinese Medicine. 2015; 43:601-620.
  140. Tang ZH, Zhang LL, Li T, Lu JH, Ma DL, Leung CH, Chen XP, Jiang HL, Wang YT, Lu JJ. Glycyrrhetinic acid induces cytoprotective autophagy via the inositol-requiring enzyme 1 alpha-c-Jun N-terminal kinase cascade in non-small cell lung cancer cells. Oncotarget. 2015; 6:43911-43926.
  141. Tang ZH, Li T, Tong YG, Chen XJ, Chen XP, Wang YT, Lu JJ. A Systematic Review of the Anticancer Properties of Compounds Isolated from Licorice (Gancao). Planta Medica. 2015; 81:1670-1687.
  142. Tan W, Zhong ZF, Wang SP, Suo ZW, Yang X, Hu XD, Wang YT. Berberine Regulated Lipid Metabolism in the Presence of C75, Compound C, and TOFA in Breast Cancer Cell Line MCF-7. Evidence-Based Complementary and Alternative Medicine. 2015.
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  144. Song YL, Jing WH, Yan R, Wang YT. Research progress of the studies on the roots of Peucedanum praeruptorum dunn (Peucedani radix). Pakistan Journal of Pharmaceutical Sciences. 2015; 28:71-81.
  145. Song MH, Ung C, Hu H, Wang YT. Community pharmacists’ perceptions about pharmaceutical care of OTC western medicine: a survey in Harbin of China. International Journal of Clinical Pharmacy. 2015; 37:1014-1020.
  146. Ni JY, Shao R, Ung COL, Wang YT, Hu YJ, Cai Y. Valuation of Pharmaceutical Patents: A Comprehensive Analytical Framework Based on Technological, Commercial, and Legal Factors. Journal of Pharmaceutical Innovation. 2015; 10:281-285.
  147. Liu QY, Wang YT, Lin LG. New insights into the anti-obesity activity of xanthones from Garcinia mangostana. Food & Function. 2015; 6:383-393.
  148. Liu JJ, Zhan XD, Wan JB, Wang YT, Wang CM. Review for carrageenan-based pharmaceutical biomaterials: Favourable physical features versus adverse biological effects. Carbohydrate Polymers. 2015; 121:27-36.
  149. Lin ZQ, Mei D, Chen MW, Wang YT, Chen XH, Wang ZY, He B, Zhang H, Wang XQ, Dai WB, Yin YX, Zhang Q. A comparative study of thermo-sensitive hydrogels with water-insoluble paclitaxel in molecule, nanocrystal and microcrystal dispersions. Nanoscale. 2015; 7:14838-14847.
  150. Li XW, Yang Y, Henry RJ, Rossetto M, Wang YT, Chen SL. Plant DNA barcoding: from gene to genome. Biological Reviews. 2015; 90:157-166.
  151. Li XW, Chen YN, Lai YF, Yang Q, Hu H, Wang YT. Sustainable Utilization of Traditional Chinese Medicine Resources: Systematic Evaluation on Different Production Modes. Evidence-Based Complementary and Alternative Medicine. 2015.
  152. Li T, Xu XH, Tang ZH, Wang YF, Leung CH, Ma DL, Chen XP, Wang YT, Chen Y, Lu JJ. Platycodin D induces apoptosis and triggers ERK- and JNK-mediated autophagy in human hepatocellular carcinoma BEL-7402 cells. Acta Pharmacologica Sinica. 2015; 36:1503-1513.
  153. Li T, Tang ZH, Xu WS, Wu GS, Wang YF, Chang LL, Zhu H, Chen XP, Wang YT, Chen Y, Lu JJ. Platycodin D triggers autophagy through activation of extracellular signal-regulated kinase in hepatocellular carcinoma HepG2 cells. European Journal of Pharmacology. 2015; 749:81-88.
  154. Li SK, Miao XQ, Wyman IW, Li Y, Zheng Y, Wang YT, Macartney DH, Wang RB. High-affinity host-guest complex of cucurbit 7 uril with a bis(thiazolium) salt. Rsc Advances. 2015; 5:56110-56115.
  155. Li RD, Wang HL, Li YB, Wang ZQ, Wang X, Wang YT, Ge ZM, Li RT. Discovery and optimization of novel dual dithiocarbamates as potent anticancer agents. European Journal of Medicinal Chemistry. 2015; 93:381-391.
  156. Leung KH, He HZ, He BY, Zhong HJ, Lin S, Wang YT, Ma DL, Leung CH. Label-free luminescence switch-on detection of hepatitis C virus NS3 helicase activity using a G-quadruplex-selective probe. Chemical Science. 2015; 6:2166-2171.
  157. Lai YF, Lu JJ, Hu H, Wang YT. Analysis of the Current Situation of Antitumor Drug Use in China: A Hospital-Based Perspective. Therapeutic Innovation & Regulatory Science. 2015; 49:181-193.
  158. Jing WH, Yan R, Wang YT. A practical strategy for chemical profiling of herbal medicines using ultra-high performance liquid chromatography coupled with hybrid triple quadrupole-linear ion trap mass spectrometry: a case study of Mori Cortex. Analytical Methods. 2015; 7:443-457.
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  160. Hu YJ, Scherngell T, Qiu L, Wang YT. R&D internationalisation patterns in the global pharmaceutical industry: evidence from a network analytic perspective. Technology Analysis & Strategic Management. 2015; 27:532-549.
  161. He TT, Ung COL, Hu H, Wang YT. Good manufacturing practice (GMP) regulation of herbal medicine in comparative research: China GMP, cGMP, WHO-GMP, PIC/S and EU-GMP. European Journal of Integrative Medicine. 2015; 7:55-66.
  162. He TT, Hu H, Wang YT. IMPLEMENTATION STATUS AND BARRIERS OF GOOD MANUFACTURING PRACTICE (GMP) FOR CHINESE PATENT MEDICINE. African Journal of Traditional Complementary and Alternative Medicines. 2015; 12:56-64.
  163. Hamano R, Wu XQ, Wang YT, Oppenheim JJ, Chen X. Characterization of MT-2 cells as a human regulatory T cell-like cell line. Cellular & Molecular Immunology. 2015; 12:780-782.
  164. Guo YP, Lin LG, Wang YT. Chemistry and pharmacology of the herb pair Flos Lonicerae japonicae-Forsythiae fructus. Chinese Medicine. 2015; 10.
  165. Guo JJ, Pan W, Chen MW, Wang CM, Wang YT. Overview of Taiwan’s indigenous ethnopharmacology in the perspective of traditional knowledge protection. Chinese Journal of Integrative Medicine. 2015; 21:949-954.
  166. Fang XB, Xu YQ, Zhang JM, Lu XH, Wang YT, Chen MW. Synthesis and Characterization of an Amphiphilic Linoleic Acid-g-Quaternary Chitosan with Low Toxicity. Journal of Nanomaterials. 2015.
  167. Ding F, Zhang QR, Ung COL, Wang YT, Han YF, Hu YJ, Qi J. An Analysis of Chemical Ingredients Network of Chinese Herbal Formulae for the Treatment of Coronary Heart Disease. Plos One. 2015; 10.
  168. Chen XJ, Tang ZH, Li XW, Xie CX, Lu JJ, Wang YT. Chemical Constituents, Quality Control, and Bioactivity of Epimedii Folium (Yinyanghuo). American Journal of Chinese Medicine. 2015; 43:783-834.
  169. Chen SR, Chen XP, Lu JJ, Wang Y, Wang YT. Potent natural products and herbal medicines for treating liver fibrosis. Chinese Medicine. 2015; 10.
  170. Chen SL, Wang YT, Zhao ZZ, Leon CJ, Henry RJ. Sustainable Utilization of TCM Resources. Evidence-Based Complementary and Alternative Medicine. 2015.
  171. Chen RE, Wang SP, Zhang JM, Chen MW, Wang YT. Aloe-emodin loaded solid lipid nanoparticles: formulation design and in vitro anti-cancer study. Drug Delivery. 2015; 22:666-674.
  172. Chen FQ, Zhang JM, Wang YT, Chen MW. Glycyrrhetinic acid-decorated and reduction-sensitive micelles for targeted cancer therapy. Journal of Controlled Release. 2015; 213:E75-E75.
  173. Chen FQ, Zhang JM, Wang L, Wang YT, Chen MW. Tumor pH(e)-triggered charge-reversal and redox-responsive nanoparticles for docetaxel delivery in hepatocellular carcinoma treatment. Nanoscale. 2015; 7:15763-15779.
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  175. Cai Y, Li XW, Li M, Chen XJ, Hu H, Ni JY, Wang YT. Traceability and Quality Control in Traditional Chinese Medicine: From Chemical Fingerprint to Two-Dimensional Barcode. Evidence-Based Complementary and Alternative Medicine. 2015.
  176. Cai Y, Fang XF, He CW, Li P, Xiao F, Wang YT, Chen MW. Cucurbitacins: A Systematic Review of the Phytochemistry and Anticancer Activity. American Journal of Chinese Medicine. 2015; 43:1331-1350.
  177. Bao JL, Huang BR, Zou LD, Chen SH, Zhang C, Zhang YL, Chen MW, Wan JB, Su HX, Wang YT, He CW. Hormetic Effect of Berberine Attenuates the Anticancer Activity of Chemotherapeutic Agents. Plos One. 2015; 10.
  178. Zhu HL, Wan JB, Wang YT, Li BC, Xiang C, He J, Li P. Medicinal compounds with antiepileptic/anticonvulsant activities. Epilepsia. 2014; 55:3-16.
  179. Zhong ZF, Tan W, Chen XP, Wang YT. Furanodiene, a natural small molecule suppresses metastatic breast cancer cell migration and invasion in vitro. European Journal of Pharmacology. 2014; 737:1-10.
  180. Zhang XJ, Su HX, He CW, Wang YT, Yang FQ, Wan JB. Discrimination of Pterocephalus hookeri collected at flowering and non-flowering stages using GC-MS-based fatty acid profiling. Analytical Methods. 2014; 6:2141-2149.
  181. Zhang JM, Li YB, Gao W, Repka MA, Wang YT, Chen MW. Andrographolide-loaded PLGA-PEG-PLGA micelles to improve its bioavailability and anticancer efficacy. Expert Opinion on Drug Delivery. 2014; 11:1367-1380.
  182. Zhang JM, Li YB, Fang XF, Zhou DM, Wang YT, Chen MW. TPGS-g-PLGA/Pluronic F68 mixed micelles for tanshinone IIA delivery in cancer therapy. International Journal of Pharmaceutics. 2014; 476:185-198.
  183. Zhan XD, Jia LX, Niu YM, Qi HX, Chen XP, Zhang QW, Zhang JF, Wang YT, Dong L, Wang CM. Targeted depletion of tumour-associated macrophages by an alendronate-glucomannan conjugate for cancer immunotherapy. Biomaterials. 2014; 35:10046-10057.
  184. Yuan YF, Song YL, Jing WH, Wang YT, Yang XY, Liu DY. Simultaneous determination of caffeine, gallic acid, theanine, (-)-epigallocatechin and (-)-epigallocatechin-3-gallate in green tea using quantitative H-1-NMR spectroscopy. Analytical Methods. 2014; 6:907-914.
  185. Yu MR, Si LL, Wang YF, Wu YM, Yu F, Jiao PX, Shi YY, Wang H, Xiao SL, Fu G, Tian K, Wang YT, Guo ZH, Ye XS, Zhang LH, Zhou DM. Discovery of Pentacyclic Triterpenoids as Potential Entry Inhibitors of Influenza Viruses. Journal of Medicinal Chemistry. 2014; 57:10058-10071.
  186. Yang Y, Wang SP, Wang YT, Wang XH, Wang Q, Chen MW. Advances in self-assembled chitosan nanomaterials for drug delivery. Biotechnology Advances. 2014; 32:1301-1316.
  187. Yang Y, Dang YY, Li Q, Lu JJ, Li XW, Wang YT. Complete Chloroplast Genome Sequence of Poisonous and Medicinal Plant Datura stramonium: Organizations and Implications for Genetic Engineering. Plos One. 2014; 9.
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  189. Yan ZX, Lin G, Ye Y, Wang YT, Yan R. A Generic Multiple Reaction Monitoring Based Approach for Plant Flavonoids Profiling Using a Triple Quadrupole Linear Ion Trap Mass Spectrometry. Journal of the American Society for Mass Spectrometry. 2014; 25:955-965.
  190. Xu WS, Li T, Wu GS, Dang YY, Hao WH, Chen XP, Lu JJ, Wang YT. Effects of Furanodiene on 95-D Lung Cancer Cells: Apoptosis, Autophagy and G1 Phase Cell Cycle Arrest. American Journal of Chinese Medicine. 2014; 42:243-255.
  191. Xu WS, Dang YY, Chen XP, Lu JJ, Wang YT. Furanodiene Presents Synergistic Anti-proliferative Activity With Paclitaxel Via Altering Cell Cycle and Integrin Signaling in 95-D Lung Cancer Cells. Phytotherapy Research. 2014; 28:296-299.
  192. Xu JC, Kong XJ, Qiu L, Geng XM, Hu YJ, Wang YT. Research and development of anti-Alzheimer’s drugs: an analysis based on technology flows measured by patent citations. Expert Opinion on Therapeutic Patents. 2014; 24:791-800.
  193. Xiang C, Li F, Zhang LD, Li BC, He J, Qin Y, Wan JB, Wang YT, Li P. DETERMINATION OF RADICAL SCAVENGERS FROM SALVIA PLANTS BY HPLC. Analytical Letters. 2014; 47:1-13.
  194. Wu WJ, Yan R, Yao MC, Zhan Y, Wang YT. Pharmacokinetics of anthraquinones in rat plasma after oral administration of a rhubarb extract. Biomedical Chromatography. 2014; 28:564-572.
  195. Wu WJ, Hu N, Zhang QW, Li YP, Li P, Yan R, Wang YT. In vitro glucuronidation of five rhubarb anthraquinones by intestinal and liver microsomes from humans and rats. Chemico-Biological Interactions. 2014; 219:18-27.
  196. Wang SP, Wang L, Shi Z, Zhong ZF, Chen MW, Wang YT. Evodiamine Synergizes with Doxorubicin in the Treatment of Chemoresistant Human Breast Cancer without Inhibiting P-Glycoprotein. Plos One. 2014; 9.
  197. Wang SP, Chen RE, Zhong ZF, Shi Z, Chen MW, Wang YT. Epigallocatechin-3-Gallate Potentiates the Effect of Curcumin in Inducing Growth Inhibition and Apoptosis of Resistant Breast Cancer Cells. American Journal of Chinese Medicine. 2014; 42:1279-1300.
  198. Wang L, Wang SP, Chen RE, Wang YP, Li H, Wang YT, Chen MW. Oridonin Loaded Solid Lipid Nanoparticles Enhanced Antitumor Activity in MCF-7 Cells. Journal of Nanomaterials. 2014.
  199. Wang L, Li HT, Wang SP, Liu R, Wu ZS, Wang CM, Wang YT, Chen MW. Enhancing the Antitumor Activity of Berberine Hydrochloride by Solid Lipid Nanoparticle Encapsulation. Aaps Pharmscitech. 2014; 15:834-844.
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  201. Tang ZH, Li T, Gao HW, Sun W, Chen XP, Wang YT, Lu JJ. Platycodin D from Platycodonis Radix enhances the anti-proliferative effects of doxorubicin on breast cancer MCF-7 and MDA-MB-231 cells. Chinese Medicine. 2014; 9.
  202. Tang ZH, Li T, Chang LL, Zhu H, Tong YG, Chen XP, Wang YT, Lu JJ. Glycyrrhetinic Acid Triggers a Protective Autophagy by Activation of Extracellular Regulated Protein Kinases in Hepatocellular Carcinoma Cells. Journal of Agricultural and Food Chemistry. 2014; 62:11910-11916.
  203. Song YL, Yan HX, Chen JF, Wang YT, Jiang Y, Tu PF. Characterization of in vitro and in vivo metabolites of carnosic acid, a natural antioxidant, by high performance liquid chromatography coupled with tandem mass spectrometry. Journal of Pharmaceutical and Biomedical Analysis. 2014; 89:183-196.
  204. Song YL, Jing WH, Yang FQ, Shi Z, Yao MC, Yan R, Wang YT. Simultaneously enantiospecific determination of (+)-trans-khellactone, ( plus /-)-praeruptorin A, ( plus /-)-praeruptorin B, (+)-praeruptorin E, and their metabolites, ( plus /-)-cis-khellactone, in rat plasma using online solid phase extraction-chiral LC-MS/MS. Journal of Pharmaceutical and Biomedical Analysis. 2014; 88:269-277.
  205. Song YL, Jing WH, Yan R, Wang YT. A pretreatment free method for the determination of seven natural products in a high-salt matrix by online guard column extraction coupled with tandem mass spectrometry. Analytical Methods. 2014; 6:623-628.
  206. Song YL, Jing WH, Yan R, Wang YT. Metabolic characterization of (+/-)-praeruptorin A in vitro and in vivo by high performance liquid chromatography coupled with hybrid triple quadrupole-linear ion trap mass spectrometry and time-of-flight mass spectrometry. Journal of Pharmaceutical and Biomedical Analysis. 2014; 90:98-110.
  207. Song YL, Jing WH, Tu PF, Wang YT. Development of enantiospecific and chemoselective methods for the determination of praeruptorin A enantiomers and their metabolites in rat plasma using chiral and achiral LC-MS/MS. Analytical Methods. 2014; 6:4831-4839.
  208. Song YL, Jing WH, Tu PF, Wang YT. Characterization of Peucedani Radix extract-derived angular-type pyranocoumarins in rats using ultra-high performance liquid chromatography coupled with hybrid triple quadrupole-linear ion trap mass spectrometry. Analytical Methods. 2014; 6:5198-5206.
  209. Song YL, Jing WH, Tu PF, Wang YT. Enantiomeric separation of angular-type pyranocoumarins from Peucedani Radix using AD-RH chiral column. Natural Product Research. 2014; 28:545-550.
  210. Song YL, Jing WH, Du G, Yang FQ, Yan R, Wang YT. Qualitative analysis and enantiospecific determination of angular-type pyranocoumarins in Peucedani Radix using achiral and chiral liquid chromatography coupled with tandem mass spectrometry. Journal of Chromatography A. 2014; 1338:24-37.
  211. Song YL, Jing WH, Chen YG, Yuan YF, Yan R, Wang YT. H-1 nuclear magnetic resonance based-metabolomic characterization of Peucedani Radix and simultaneous determination of praeruptorin A and praeruptorin B. Journal of Pharmaceutical and Biomedical Analysis. 2014; 93:86-94.
  212. Song J, Wang YC, Song YL, Chan H, Bi C, Yang X, Yan R, Wang YT, Zheng Y. Development and Characterisation of Ursolic Acid Nanocrystals Without Stabiliser Having Improved Dissolution Rate and In Vitro Anticancer Activity. Aaps Pharmscitech. 2014; 15:11-19.
  213. Shen DY, Wei JC, Wan JB, Huang XJ, Xiang C, Li BC, Zhang QW, Wang YT, Li P. Four new C-21 steroidal glycosides from Cynanchum otophyllum Schneid. Phytochemistry Letters. 2014; 9:86-91.
  214. Qiu L, Chen ZY, Lu DY, Hu H, Wang YT. Public funding and private investment for R&D: a survey in China’s pharmaceutical industry. Health Research Policy and Systems. 2014; 12.
  215. Pratheeshkumar P, Son YO, Wang X, Divya SP, Joseph B, Hitron JA, Wang L, Kim D, Yin YQ, Roy RV, Lu J, Zhang Z, Wang YT, Shi XL. Cyanidin-3-glucoside inhibits UVB-induced oxidative damage and inflammation by regulating MAP kinase and NF-kappa B signaling pathways in SKH-1 hairless mice skin. Toxicology and Applied Pharmacology. 2014; 280:127-137.
  216. Pratheeshkumar P, Son YO, Divya SP, Roy RV, Hitron JA, Wang L, Kim D, Dai J, Asha P, Zhang Z, Wang YT, Shi XL. Luteolin inhibits Cr(VI)-induced malignant cell transformation of human lung epithelial cells by targeting ROS mediated multiple cell signaling pathways. Toxicology and Applied Pharmacology. 2014; 281:230-241.
  217. Niu YM, Bai J, Kamm RD, Wang YT, Wang CM. Validating Antimetastatic Effects of Natural Products in an Engineered Microfluidic Platform Mimicking Tumor Microenvironment. Molecular Pharmaceutics. 2014; 11:2022-2029.
  218. Ni JY, Xu JC, Hu YJ, Su L, Wang YT. Cross-regional Pharmaceutical Technology Transfer in China Patterns and Proposed Investment Strategies. Therapeutic Innovation & Regulatory Science. 2014; 48:226-235.
  219. Ma ZQ, Hu H, He TT, Guo H, Zhang MY, Chen MW, Wang YT. AN ASSESSMENT OF TRADITIONAL UIGHUR MEDICINE IN CURRENT XINJIANG REGION (CHINA). African Journal of Traditional Complementary and Alternative Medicines. 2014; 11:301-314.
  220. Liu LJ, Leung KH, Chan DSH, Wang YT, Ma DL, Leung CH. Identification of a natural product-like STAT3 dimerization inhibitor by structure-based virtual screening. Cell Death & Disease. 2014; 5.
  221. Liu JJ, Wang YT, Qiu L, Yu YY, Wang CM. Saponins of Panax notoginseng: chemistry, cellular targets and therapeutic opportunities in cardiovascular diseases. Expert Opinion on Investigational Drugs. 2014; 23:523-539.
  222. Lin LG, Xie H, Wang YT, Ding J, Ye Y. Chemical Constituents from the Heartwood of Haematoxylon campechianum as Protein Tyrosine Kinase Inhibitors. Chemistry & Biodiversity. 2014; 11:776-783.
  223. Lin LG, Ke CQ, Wang YT, Ye Y. Two New Alkaloids from Roots of Stemona tuberosa. Records of Natural Products. 2014; 8:317-322.
  224. Li T, Xu WS, Wu GS, Chen XP, Wang YT, Lu JJ. Platycodin D Induces Apoptosis, and Inhibits Adhesion, Migration and Invasion in HepG2 Hepatocellular Carcinoma Cells. Asian Pacific Journal of Cancer Prevention. 2014; 15:1745-1749.
  225. Huang L, Wu Q, Li YH, Wang YT, Bi HC. PXR-Mediated Upregulation of CYP3A Expression by Herb Compound Praeruptorin C from Peucedanum praeruptorum Dunn (vol 2013, 156574, 2013). Evidence-Based Complementary and Alternative Medicine. 2014.
  226. Huang L, Huang M, Li YH, Li RM, Zeng Y, Kuang SY, Zhang L, Wang YT, Bi HC. Up-regulatation of CYP3A expression through pregnent X receptor by praeruptorin D isolated from Peucedanum praeruptorum Dunn (vol 148, pg 596, 2013). Journal of Ethnopharmacology. 2014; 155:1399-1399.
  227. Hu N, Mei M, Ruan JQ, Wu WJ, Wang YT, Yan R. Regioselective Glucuronidation of Oxyresveratrol, a Natural Hydroxystilbene, by Human Liver and Intestinal Microsomes and Recombinant UGTs. Drug Metabolism and Pharmacokinetics. 2014; 29:229-236.
  228. Chen YG, Song YL, Wang Y, Yuan YF, Huang XJ, Ye WC, Wang YT, Zhang QW. Metabolic differentiations of Pueraria lobata and Pueraria thomsonii using H-1 NMR spectroscopy and multivariate statistical analysis. Journal of Pharmaceutical and Biomedical Analysis. 2014; 93:51-58.
  229. Chen XP, Guo JJ, Bao JL, Lu JJ, Wang YT. The Anticancer Properties of Salvia Miltiorrhiza Bunge (Danshen): A Systematic Review. Medicinal Research Reviews. 2014; 34:768-794.
  230. Chen RE, Zhang JM, Hu YY, Wang SP, Chen MW, Wang YT. Potential Antineoplastic Effects of Aloe-emodin: A Comprehensive Review. American Journal of Chinese Medicine. 2014; 42:275-288.
  231. Chen MW, Chen WR, Zhang JM, Long XY, Wang YT. Lobelia chinensis: chemical constituents and anticancer activity perspective. Chinese Journal of Natural Medicines. 2014; 12:103-107.
  232. Cao JL, Wei JC, Chen MW, Su HX, Wan JB, Wang YT, Li P. Application of two-dimensional chromatography in the analysis of Chinese herbal medicines. Journal of Chromatography A. 2014; 1371:1-14.
  233. Zhao HY, Hu H, Wang YT. Comparative metabolism and stability of andrographolide in liver microsomes from humans, dogs and rats using ultra-performance liquid chromatography coupled with triple-quadrupole and Fourier transform ion cyclotron resonance mass spectrometry. Rapid Communications in Mass Spectrometry. 2013; 27:1385-1392.
  234. Zhang XJ, Huang LL, Cai XJ, Li P, Wang YT, Wan JB. Fatty acid variability in three medicinal herbs of Panax species. Chemistry Central Journal. 2013; 7.
  235. Yao XL, Ye CH, Liu Q, Wan JB, Zhen J, Xiang AP, Li WQ, Wang YT, Su HX, Lu XL. Motoneuron Differentiation of Induced Pluripotent Stem Cells from SOD1G93A Mice. Plos One. 2013; 8.
  236. Xu ZT, Wu GS, Wei X, Chen XP, Wang YT, Chen LD. Celastrol Induced DNA Damage, Cell Cycle Arrest, and Apoptosis in Human Rheumatoid Fibroblast-Like Synovial Cells. American Journal of Chinese Medicine. 2013; 41:615-628.
  237. Xu WS, Li T, Wu GS, Dang YY, Chen XP, Lu JJ, Wang YT. Furanodiene induces G1 cell cycle arrest and activates the signaling molecules regulating apoptosis and autophagy, and slightly inhibits key steps of cell metastasis in 95-D lung cancer cells. Acta Pharmacologica Sinica. 2013; 34:17-17.
  238. Wu GS, Song YL, Yin ZQ, Guo JJ, Wang SP, Zhao WW, Chen XP, Zhang QW, Lu JJ, Wang YT. Ganoderiol A-enriched extract suppresses migration and adhesion via inhibiting FAK-SRC-paxillin cascade pathway in MDA-MB-231 cells. Acta Pharmacologica Sinica. 2013; 34:32-32.
  239. Wu GS, Song YL, Yin ZQ, Guo JJ, Wang SP, Zhao WW, Chen XP, Zhang QW, Lu JJ, Wang YT. Ganoderiol A-Enriched Extract Suppresses Migration and Adhesion of MDA-MB-231 Cells by Inhibiting FAK-SRC-Paxillin Cascade Pathway. Plos One. 2013; 8.
  240. Wu GS, Lu JJ, Guo JJ, Huang MQ, Gan L, Chen XP, Wang YT. Synergistic anti-cancer activity of the combination of dihydroartemisinin and doxorubicin in breast cancer cells. Pharmacological Reports. 2013; 65:453-459.
  241. Wu GS, Guo JJ, Bao JL, Li XW, Chen XP, Lu JJ, Wang YT. Anti-cancer properties of triterpenoids isolated from Ganoderma lucidum – a review. Expert Opinion on Investigational Drugs. 2013; 22:981-992.
  242. Wang SP, Zhong ZF, Wan JB, Tan W, Wu GS, Chen MW, Wang YT. Oridonin Induces Apoptosis, Inhibits Migration and Invasion on Highly-Metastatic Human Breast Cancer Cells. American Journal of Chinese Medicine. 2013; 41:177-196.
  243. Wang SP, Zhang JM, Chen MW, Wang YT. Delivering flavonoids into solid tumors using nanotechnologies. Expert Opinion on Drug Delivery. 2013; 10:1411-1428.
  244. Wang L, Zhang JM, Hong YL, Feng Y, Chen MW, Wang YT. Phytochemical and Pharmacological Review of Da Chuanxiong Formula: A Famous Herb Pair Composed of Chuanxiong Rhizoma and Gastrodiae Rhizoma for Headache. Evidence-Based Complementary and Alternative Medicine. 2013.
  245. Wan JB, Li P, Yang RL, Zhang QW, Wang YT. SEPARATION AND PURIFICATION OF 5 SAPONINS FROM Panax Notoginseng BY PREPARATIVE HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY. Journal of Liquid Chromatography & Related Technologies. 2013; 36:406-417.
  246. Wan JB, Bai X, Cai XJ, Rao Y, Wang YS, Wang YT. Chemical differentiation of Da-Cheng-Qi-Tang, a Chinese medicine formula, prepared by traditional and modern decoction methods using UPLC/Q-TOFMS-based metabolomics approach. Journal of Pharmaceutical and Biomedical Analysis. 2013; 83:34-42.
  247. Su HX, Wang LH, Huang WH, Qin DJ, Cai JL, Yao XL, Feng CQ, Li ZY, Wang YT, So KF, Pan GJ, Wu WT, Pei DQ. Immediate expression of Cdh2 is essential for efficient neural differentiation of mouse induced pluripotent stem cells. Stem Cell Research. 2013; 10:338-348.
  248. Shen H, Leung WI, Ruan JQ, Li SL, Lei JPC, Wang YT, Yan R. Biotransformation of ginsenoside Rb1 via the gypenoside pathway by human gut bacteria. Chinese Medicine. 2013; 8.
  249. Lu JJ, Bao JL, Wu GS, Xu WS, Huang MQ, Chen XP, Wang YT. Quinones Derived from Plant Secondary Metabolites as Anti-cancer Agents. Anti-Cancer Agents in Medicinal Chemistry. 2013; 13:456-463.
  250. Li YB, Zhong ZF, Chen MW, Bao JL, Wu GS, Zhang QW, Lee SMY, Hoi PM, Wang YT. Bisdemethoxycurcumin Increases Sirt1 to Antagonize t-BHP-Induced Premature Senescence in WI38 Fibroblast Cells. Evidence-Based Complementary and Alternative Medicine. 2013.
  251. Li YB, Wang ZQ, Yan X, Chen MW, Bao JL, Wu GS, Ge ZM, Zhou DM, Wang YT, Li RT. IC-4, a new irreversible EGFR inhibitor, exhibits prominent anti-tumor and anti-angiogenesis activities. Cancer Letters. 2013; 340:88-96.
  252. Li YB, Gao JL, Zhong ZF, Hoi PM, Lee SMY, Wang YT. Bisdemethoxycurcumin suppresses MCF-7 cells proliferation by inducing ROS accumulation and modulating senescence-related pathways. Pharmacological Reports. 2013; 65:700-709.
  253. Li XW, Gao HH, Wang YT, Song JY, Henry R, Wu HZ, Hu ZG, Yao H, Luo HM, Luo K, Pan HL, Chen SL. Complete chloroplast genome sequence of Magnolia grandiflora and comparative analysis with related species. Science China-Life Sciences. 2013; 56:189-198.
  254. Jing WH, Song YL, Yan R, Wang YT. Identification of cytochrome P450 isoenzymes involved in metabolism of (+)-praeruptorin A, a calcium channel blocker, by human liver microsomes using ultra high-performance liquid chromatography coupled with tandem mass spectrometry. Journal of Pharmaceutical and Biomedical Analysis. 2013; 77:175-188.
  255. Huang L, Wu Q, Li YH, Wang YT, Bi HC. PXR-Mediated Upregulation of CYP3A Expression by Herb Compound Praeruptorin C from Peucedanum praeruptorum Dunn. Evidence-Based Complementary and Alternative Medicine. 2013.
  256. Huang L, Huang M, Li YH, Li RM, Zeng Y, Kuang SY, Zhang L, Wang YT, Bi HC. Up-regulatation of CYP3A expression through pregnent X receptor by praeruptorin D isolated from Peucedanum praeruptorum Dunn. Journal of Ethnopharmacology. 2013; 148:596-602.
  1. Huang L, Bi HC, Li YH, Zhang JQ, Kuang SY, Zhang L, Wang YT, Huang M. Regulation of Human Pregnane X Receptor and its Target Gene Cytochrome P450 3A by Praeruptorin A Isolated from the Herbal Medicine Peucedanum praeruptorum. Planta Medica. 2013; 79:1509-1515.
  2. Hu YY, Wang SP, Wu X, Zhang JM, Chen R, Chen MW, Wang YT. Chinese herbal medicine-derived compounds for cancer therapy: A focus on hepatocellular carcinoma. Journal of Ethnopharmacology. 2013; 149:601-612.
  3. Hu YJ, Scherngell T, Man SN, Wang YT. Is the United States Still Dominant in the Global Pharmaceutical Innovation Network? Plos One. 2013; 8.
  4. Han W, Wang SP, Liang RX, Wang L, Chen MW, Li H, Wang YT. Non-ionic surfactant vesicles simultaneously enhance antitumor activity and reduce the toxicity of cantharidin. International Journal of Nanomedicine. 2013; 8:2187-2196.
  5. Guo Y, Hu YJ, Zheng ML, Wang YT. Patent indicators: a window to pharmaceutical market success. Expert Opinion on Therapeutic Patents. 2013; 23:765-771.
  6. Gao L, Fang JS, Bai XY, Zhou D, Wang YT, Liu AL, Du GH. In silico Target Fishing for the Potential Targets and Molecular Mechanisms of Baicalein as an Antiparkinsonian Agent: Discovery of the Protective Effects on NMDA Receptor-Mediated Neurotoxicity. Chemical Biology & Drug Design. 2013; 81:675-687.
  7. Chen XP, Lu JJ, Bao JL, Guo JJ, Shi JS, Wang YT. Adiponectin: A biomarker for rheumatoid arthritis? Cytokine & Growth Factor Reviews. 2013; 24:83-89.
  8. Chen MW, Zhang JM, Lai YF, Wang SP, Li P, Xiao J, Fu CM, Hu H, Wang YT. Analysis of Pogostemon cablin from pharmaceutical research to market performances. Expert Opinion on Investigational Drugs. 2013; 22:245-257.
  9. Chen MW, Chen RE, Wang SP, Tan W, Hu YY, Peng XS, Wang YT. Chemical components, pharmacological properties, and nanoparticulate delivery systems of Brucea javanica. International Journal of Nanomedicine. 2013; 8:85-92.
  10. Zhou RN, Song YL, Ruan JQ, Wang YT, Yan R. Pharmacokinetic Evidence on the Contribution of Intestinal Bacterial Conversion to Beneficial Effects of Astragaloside IV, a Marker Compound of Astragali Radix, in Traditional Oral Use of the Herb. Drug Metabolism and Pharmacokinetics. 2012; 27:586-597.
  11. Zhong ZF, Li YB, Wang SP, Tan W, Chen XP, Chen MW, Wang YT. Furanodiene enhances tamoxifen-induced growth inhibitory activity of ERa-positive breast cancer cells in a PPAR gamma independent manner. Journal of Cellular Biochemistry. 2012; 113:2643-2651.
  12. Zhong ZF, Hoi PM, Wu GS, Xu ZT, Tan W, Chen XP, Cui L, Wu T, Wang YT. Anti-angiogenic effect of furanodiene on HUVECs in vitro and on zebrafish in vivo. Journal of Ethnopharmacology. 2012; 141:721-727.
  13. Zhong ZF, Dang YY, Yuan X, Guo W, Li YB, Tan W, Cui JR, Lu JJ, Zhang QW, Chen XP, Wang YT. Furanodiene, a Natural Product, Inhibits Breast Cancer Growth Both in vitro and in vivo. Cellular Physiology and Biochemistry. 2012; 30:778-790.
  14. Zhao BX, Wang Y, Zhang DM, Huang XJ, Bai LL, Yan Y, Chen JM, Lu TB, Wang YT, Zhang QW, Ye WC. Virosaines A and B, Two New Birdcage-Shaped Securinega Alkaloids with an Unprecedented Skeleton from Flueggea virosa. Organic Letters. 2012; 14:3096-3099.
  15. Zhang H, Zhang QW, Wang L, Zhang XQ, Ye WC, Wang YT. Two new anthraquinone malonylglucosides from Polygonum cuspidatum. Natural Product Research. 2012; 26:1323-1327.
  16. Yi Y, Zhang QW, Li SL, Wang Y, Ye WC, Zhao J, Wang YT. Simultaneous quantification of major flavonoids in “Bawanghua”, the edible flower of Hylocereus undatus using pressurised liquid extraction and high performance liquid chromatography. Food Chemistry. 2012; 135:528-533.
  17. Yang F, Zhou WL, Liu AL, Qin HL, Lee SMY, Wang YT, Du GH. The Protective Effect of 3-Deoxysappanchalcone on In Vitro Influenza Virus-induced Apoptosis and Inflammation. Planta Medica. 2012; 78:968-973.
  18. Xu ZT, Chen XP, Fu S, Bao JL, Dang YY, Huang MQ, Chen LD, Wang YT. Dehydrocorydaline Inhibits Breast Cancer Cells Proliferation by Inducing Apoptosis in MCF-7 Cells. American Journal of Chinese Medicine. 2012; 40:177-185.
  19. Xu ZT, Chen XP, Fu S, Bao JL, Dang YY, Huang MQ, Chen LD, Wang YT. Dehydrocorydaline Inhibits Breast Cancer Cells Proliferation by Inducing Apoptosis in MCF-7 Cells (vol 40, pg 177, 2012). American Journal of Chinese Medicine. 2012; 40:1323-1323.
  20. Xu WS, Dang YY, Guo JJ, Wu GS, Lu JJ, Chen XP, Wang YT. Furanodiene Induces Endoplasmic Reticulum Stress and Presents Antiproliferative Activities in Lung Cancer Cells. Evidence-Based Complementary and Alternative Medicine. 2012.
  21. Wu GS, Qian ZM, Guo JJ, Hu DJ, Bao JL, Xie J, Xu WS, Lu JJ, Chen XP, Wang YT. Ganoderma lucidum Extract Induces G1 Cell Cycle Arrest, and Apoptosis in Human Breast Cancer Cells. American Journal of Chinese Medicine. 2012; 40:631-642.
  22. Wu GS, Lu JJ, Guo JJ, Li YB, Tan W, Dang YY, Zhong ZF, Xu ZT, Chen XP, Wang YT. Ganoderic acid DM, a natural triterpenoid, induces DNA damage, G1 cell cycle arrest and apoptosis in human breast cancer cells. Fitoterapia. 2012; 83:408-414.
  23. Wang SP, Wu X, Tan M, Gong J, Tan W, Bian BL, Chen MW, Wang YT. Fighting fire with fire: Poisonous Chinese herbal medicine for cancer therapy. Journal of Ethnopharmacology. 2012; 140:33-45.
  24. Wang SP, Hu YY, Tan W, Wu X, Chen RE, Cao JL, Chen MW, Wang YT. Compatibility art of traditional Chinese medicine: From the perspective of herb pairs. Journal of Ethnopharmacology. 2012; 143:412-423.
  25. Wang SP, Chen TK, Chen RE, Hu YY, Chen MW, Wang YT. Emodin loaded solid lipid nanoparticles: Preparation, characterization and antitumor activity studies. International Journal of Pharmaceutics. 2012; 430:238-246.
  26. Wan JB, Zhang QW, Hong SJ, Li P, Li SP, Wang YT. Chemical Investigation of Saponins in Different Parts of Panax notoginseng by Pressurized Liquid Extraction and Liquid Chromatography-Electrospray Ionization-Tandem Mass Spectrometry. Molecules. 2012; 17:5836-5853.
  27. Song YL, Zhang QW, Li YP, Yan R, Wang YT. Enantioseparation and Absolute Configuration Determination of Angular-Type Pyranocoumarins from Peucedani Radix Using Enzymatic Hydrolysis and Chiral HPLC-MS/MS Analysis. Molecules. 2012; 17:4236-4251.
  28. Song YL, Jing WH, Zhao HY, Yan R, Li PT, Wang YT. Stereoselective metabolism of (+/-)-praeruptorin A, a calcium channel blocker from Peucedani Radix, in pooled liver microsomes of rats and humans. Xenobiotica. 2012; 42:221-237.
  29. Mei M, Ruan JQ, Wu WJ, Zhou RN, Lei JPC, Zhao HY, Yan R, Wang YT. In Vitro Pharmacokinetic Characterization of Mulberroside A, the Main Polyhydroxylated Stilbene in Mulberry (Morus alba L.), and Its Bacterial Metabolite Oxyresveratrol in Traditional Oral Use. Journal of Agricultural and Food Chemistry. 2012; 60:2299-2308.
  30. Lu JJ, Pan W, Hu YJ, Wang YT. Multi-Target Drugs: The Trend of Drug Research and Development. Plos One. 2012; 7.
  31. Lu JJ, Dang YY, Huang M, Xu WS, Chen XP, Wang YT. Anti-cancer properties of terpenoids isolated from Rhizoma Curcumae – A review. Journal of Ethnopharmacology. 2012; 143:406-411.
  32. Lu JJ, Bao JL, Chen XP, Huang M, Wang YT. Alkaloids Isolated from Natural Herbs as the Anticancer Agents. Evidence-Based Complementary and Alternative Medicine. 2012.
  33. Li F, Zhang LD, Li BC, Yang J, Yu H, Wan JB, Wang YT, Li P. Screening of free radical scavengers from Erigeron breviscapus using on-line HPLC-ABTS/DPPH based assay and mass spectrometer detection. Free Radical Research. 2012; 46:286-294.
  34. Huang MQ, Xie YL, Chen LD, Chu KD, Wu SS, Lu JJ, Chen XP, Wang YT, Lai XP. Antidiabetic Effect of the Total Polyphenolic Acids Fraction from Salvia miltiorrhiza Bunge in Diabetic Rats. Phytotherapy Research. 2012; 26:944-948.
  35. Huang M, Lu JJ, Huang MQ, Bao JL, Chen XP, Wang YT. Terpenoids: natural products for cancer therapy. Expert Opinion on Investigational Drugs. 2012; 21:1801-1818.
  36. Gong J, Chen MW, Zheng Y, Wang SP, Wang YT. Polymeric micelles drug delivery system in oncology. Journal of Controlled Release. 2012; 159:312-323.
  37. Du G, Xiao Y, Yang HR, Wang L, Song YL, Wang YT. Rapid determination of pesticide residues in herbs using selective pressurized liquid extraction and fast gas chromatography coupled with mass spectrometry. Journal of Separation Science. 2012; 35:1922-1932.
  38. Ding RB, Tian K, Huang LL, He CW, Jiang Y, Wang YT, Wan JB. Herbal medicines for the prevention of alcoholic liver disease: A review. Journal of Ethnopharmacology. 2012; 144:457-465.
  39. Chen XP, Bao JL, Guo JJ, Ding Q, Lu JJ, Huang MQ, Wang YT. Biological activities and potential molecular targets of cucurbitacins: a focus on cancer. Anti-Cancer Drugs. 2012; 23:777-787.
  40. Chen MW, Zhou YF, Huang JJ, Zhu P, Peng XS, Wang YT. Liposome-Based Delivery Systems in Plant Polysaccharides. Journal of Nanomaterials. 2012.
  41. Chen MW, Zhang JM, Yu SQ, Wang SP, Zhang ZJ, Chen JQ, Xiao J, Wang YT. Anti-Lung-Cancer Activity and Liposome-Based Delivery Systems of beta-Elemene. Evidence-Based Complementary and Alternative Medicine. 2012.
  42. Zhong ZF, Chen XP, Tan W, Xu ZT, Zhou KY, Wu T, Cui L, Wang YT. Germacrone inhibits the proliferation of breast cancer cell lines by inducing cell cycle arrest and promoting apoptosis. European Journal of Pharmacology. 2011; 667:50-55.
  43. Yeh JC, Cindrova-Davies T, Belleri M, Morbidelli L, Miller N, Cho CWC, Chan K, Wang YT, Luo GA, Ziche M, Presta M, Charnock-Jones DS, Fan TP. The natural compound n-butylidenephthalide derived from the volatile oil of Radix Angelica sinensis inhibits angiogenesis in vitro and in vivo. Angiogenesis. 2011; 14:187-197.
  44. Xu ZT, Chen XU, Zhong ZF, Chen LD, Wang YT. Ganoderma lucidum Polysaccharides: Immunomodulation and Potential Anti-Tumor Activities. American Journal of Chinese Medicine. 2011; 39:15-27.
  45. Xu ZT, Chen XP, Zhang QW, Chen LDA, Wang YT. Corydalis yanhusuo WT Wang Extract Inhibits MCF-7 Cell Proliferation by Inducing Cell Cycle G2/M Arrest. American Journal of Chinese Medicine. 2011; 39:579-586.
  46. Wu WJ, Song YL, Li YP, Yan R, Wang YT. Characterization of in vitro glucuronidation of five anthraquinones from Rhubarb. Drug Metabolism Reviews. 2011; 43:52-52.
  47. Wang SP, Tan M, Zhong ZF, Chen MW, Wang YT. Nanotechnologies for Curcumin: An Ancient Puzzler Meets Modern Solutions. Journal of Nanomaterials. 2011.
  48. Wang N, Wan JB, Chan SW, Deng YH, Yu N, Zhang QW, Wang YT, Lee SMY. Comparative study on saponin fractions from Panax notoginseng inhibiting inflammation-induced endothelial adhesion molecule expression and monocyte adhesion. Chinese Medicine. 2011; 6.
  49. Tan W, Lu JJ, Huang MQ, Li YB, Chen MW, Wu GS, Gong J, Zhong ZF, Xu ZT, Dang YY, Guo JJ, Chen XP, Wang YT. Anti-cancer natural products isolated from chinese medicinal herbs. Chinese Medicine. 2011; 6.
  50. Song YL, Yan R, Jing WH, Zhao HY, Wang YT. Characterization of metabolism of (+)-praeruptorin B and (+)-praeruptorin E in human and rat liver microsomes by liquid chromatography coupled with ion trap mass spectrometry and time-of-flight mass spectrometry. Rapid Communications in Mass Spectrometry. 2011; 25:719-730.
  51. Liu YH, Mo SL, Bi HC, Hu BF, Li CG, Wang YT, Huang L, Huang M, Duan W, Liu JP, Wei MQ, Zhou SF. Regulation of human pregnane X receptor and its target gene cytochrome P450 3A4 by Chinese herbal compounds and a molecular docking study. Xenobiotica. 2011; 41:259-280.
  52. Li ZH, Alex D, Siu SO, Chu IK, Renn J, Winkler C, Lou S, Tsui SKW, Zhao HY, Yan WR, Mahady GB, Li GH, Kwan YW, Wang YT, Lee SMY. Combined in vivo imaging and omics approaches reveal metabolism of icaritin and its glycosides in zebrafish larvae. Molecular Biosystems. 2011; 7:2128-2138.
  53. Li YB, Lin ZQ, Zhang ZJ, Wang MW, Zhang HA, Zhang Q, Lee SMY, Wang YT, Hoi PM. Protective, Antioxidative and Antiapoptotic Effects of 2-Methoxy-6-Acetyl-7-Methyljuglone from Polygonum cuspidatum in PC12 Cells. Planta Medica. 2011; 77:354-361.
  54. Li YB, Gao JL, Lee SMY, Zhang QW, Hoi PM, Wang YT. Bisdemethoxycurcumin protects endothelial cells against t-BHP-induced cell damage by regulating the phosphorylation level of ERK1/2 and Akt. International Journal of Molecular Medicine. 2011; 27:205-211.
  55. Li GH, Zhang QW, Wang L, Zhang XQ, Ye WC, Wang YT. New Isoflavone C-Glycosides from Pueraria lobata. Helvetica Chimica Acta. 2011; 94:423-428.
  56. Jing WH, Song YL, Yan R, Bi HC, Li PT, Wang YT. Transport and metabolism of (+/-)-praeruptorin A in Caco-2 cell monolayers. Xenobiotica. 2011; 41:71-81.
  57. Huang L, Bi HC, Liu YH, Wang YT, Xue XP, Huang M. CAR-mediated Up-regulation of CYP3A4 Expression in LS174T Cells by Chinese Herbal Compounds. Drug Metabolism and Pharmacokinetics. 2011; 26:331-340.
  58. He BC, Gao JL, Luo XJ, Luo JY, Shen JK, Wang LY, Zhou QX, Wang YT, Luu HH, Haydon RC, Wang CZ, Du W, Yuan CS, He TC, Zhang BQ. Ginsenoside Rg3 inhibits colorectal tumor growth through the down-regulation of Wnt/beta-catenin signaling. International Journal of Oncology. 2011; 38:437-445.
  59. Du G, Zhao HY, Song YL, Zhang QW, Wang YT. Rapid simultaneous determination of isoflavones in Radix puerariae using high-performance liquid chromatography-triple quadrupole mass spectrometry with novel shell-type column. Journal of Separation Science. 2011; 34:2576-2585.
  60. Du G, Song YL, Wang YT. Rapid simultaneous determination of multiple pesticide residues in traditional Chinese medicines using programmed temperature vaporizer injection-fast gas chromatography coupled with mass spectrometry. Journal of Separation Science. 2011; 34:3372-3382.
  61. Deng YH, Alex D, Huang HQ, Wang N, Yu N, Wang YT, Leung GPH, Lee SMY. Inhibition of TNF-alpha-mediated Endothelial Cell-Monocyte Cell Adhesion and Adhesion Molecules Expression by the Resveratrol Derivative, trans-3,5,4 ‘-Trimethoxystilbene. Phytotherapy Research. 2011; 25:451-457.
  62. Chen XP, Zhong ZF, Xu ZT, Chen LD, Wang YT. No protective effect of curcumin on hydrogen peroxide-induced cytotoxicity in HepG2 cells. Pharmacological Reports. 2011; 63:724-732.
  63. Chen XP, Xu ZT, Wang YT. Recent advances in breast cancer metastasis suppressor 1. International Journal of Biological Markers. 2011; 26:1-8.
  64. Chen XP, Wang YT. Adiponectin and breast cancer. Medical Oncology. 2011; 28:1288-1295.
  65. Chen XP, Pei LX, Zhong ZF, Guo JJ, Zhang QW, Wang YT. Anti-tumor potential of ethanol extract of Curcuma phaeocaulis Valeton against breast cancer cells. Phytomedicine. 2011; 18:1238-1243.
  66. Chen MW, Zhong ZF, Tan W, Wang SP, Wang YT. Recent advances in nanoparticle formulation of oleanolic acid. Chinese Medicine. 2011; 6.
  67. Chen MW, Wang SP, Tan M, Wang YT. Applications of Nanoparticles in Herbal Medicine: Zedoary Turmeric Oil and Its Active Compound beta-Elemene. American Journal of Chinese Medicine. 2011; 39:1093-1102.
  68. Wan JB, Zhang QW, Hong SJ, Guan J, Ye WC, Li SP, Lee MYS, Wang YT. 5,6-Didehydroginsenosides from the Roots of Panax notoginseng. Molecules. 2010; 15:8169-8176.
  69. Ruan JQ, Wang YT, Yan R. In Vivo and In Vitro Pharmacokinetic Characterization of Calycosin. Drug Metabolism Reviews. 2010; 42:262-263.
  70. Ruan JQ, Leong WI, Yan R, Wang YT. Characterization of Metabolism and in Vitro Permeability Study of Notoginsenoside R1 from Radix Notoginseng. Journal of Agricultural and Food Chemistry. 2010; 58:5770-5776.
  71. Qin XL, Bi HC, Wang XD, Li JL, Wang Y, Xue XP, Chen X, Wang CX, Xu LJ, Wang YT, Huang M. Mechanistic understanding of the different effects of Wuzhi Tablet (Schisandra sphenanthera extract) on the absorption and first-pass intestinal and hepatic metabolism of Tacrolimus (FK506). International Journal of Pharmaceutics. 2010; 389:114-121.
  72. Liang QY, Chow AHL, Wang YT, Tong HHY, Zheng Y. Removal of toxic aristolochic acid components from Aristolochia plants by supercritical fluid extraction. Separation and Purification Technology. 2010; 72:269-274.
  73. Hu YM, Wang YT, Sze SCW, Tsang KW, Wong HK, Liu Q, Zhong LD, Tong Y. Identification of the major chemical constituents and their metabolites in rat plasma and various organs after oral administration of effective Erxian Decoction (EXD) fraction by liquid chromatography-mass spectrometry. Biomedical Chromatography. 2010; 24:479-489.
  74. Du G, Zhao HY, Zhang QW, Li GH, Yang FQ, Wang Y, Li YC, Wang YT. A rapid method for simultaneous determination of 14 phenolic compounds in Radix Puerariae using microwave-assisted extraction and ultra high performance liquid chromatography coupled with diode array detection and time-of-flight mass spectrometry. Journal of Chromatography A. 2010; 1217:705-714.
  75. Dang YY, Li XC, Zhang QW, Li SP, Wang YT. Preparative isolation and purification of six volatile compounds from essential oil of Curcuma wenyujin using high-performance centrifugal partition chromatography. Journal of Separation Science. 2010; 33:1658-1664.
  76. Chen XP, Zhong ZF, Xu ZT, Chen LD, Wang YT. 2 ‘,7 ‘-Dichlorodihydrofluorescein as a fluorescent probe for reactive oxygen species measurement: Forty years of application and controversy. Free Radical Research. 2010; 44:587-604.
  77. Chen XJ, Yang FQ, Wang YT, Li SP. CE and CEC of nucleosides and nucleotides in food materials. Electrophoresis. 2010; 31:2092-2105.

Advisory committee / Panel member

  • Executive Director and Deputy Secretary-General, World Federation of Chinese Medicine Societies
  • Vice President, Professional Committee of Pharmacology, World Federation of Chinese Medicine Societies
  • Vice President, Standardization Committee, World Federation of Chinese Medicine Societies
  • Secretary-General, International Society of Chinese Medicine
  • Senior consultant of the FP7 EU-China Consortium on Modernisation of Chinese medicine research (GP-TCM)
  • Executive Chair, Research Association of Senior Education of Chinese Medicine
  • Standing Committee Member, Chinese Pharmacological Society (CNPHAR)
  • Member, Expert Committee of National Drug Evaluation of China
  • Member, Expert Committee of Major Program of National Natural Science Foundation of China
  • Member, National Committee on Assessment of State Science and Technology Award
  • Member, National Committee on Assessment for the Secrecy of Science and Technology
  • Member, National Assessment Committee on Protective Chinese Medicine