Email

spli@um.edu.mo

Tel

(853) 8822 4692

Office

N22-6008

Consultation Hours

Wed: 11:00-12:00
Thu: 11:00-12:00

Shaoping LI 李紹平

Distinguished Professor
Deputy Director, State Key Laboratory of Quality Research in Chinese Medicines (University of Macau)
Director, Macao Centre for Testing of Chinese Medicine, University of Macau
Editor, Journal of Pharmaceutical and Biomedical Analysis

Academic Qualifications

MSc, PhD, China Pharmaceutical University

Teaching

HSCI3012Pharmaceutical Analysis
CMED716Quality Control of Chinese MedicineM.Sc. Course
CMED809Quality Research of Chinese MedicinePhD Course
CMED822Advanced Pharmaceutical AnalysisPhD Course

Research Interests

  • Glycol-analysis, especially saccharide mapping in quality control of herbal glycans.
  • Standard development of Chinese medicines.
  • Development of quality control methods, including HPLC, LC-MS, CE, CEC and GC-MS, for Chinese medicines.
  • Culture, fermentation, active ingredients and quality control of medicinal mushroom, such as Cordyceps spp., Ganoderma spp..


We are looking for Post-doctor, PhD students and master students who are interested in herbal glycochemistry, glycobiology, instrumental analysis and Chinese medicines. For further information, please contact Prof. Li (spli@umac.mo).

  • National Key R & D Plan Key Project of Modernization of Chinese Medicines: Quality evaluation-oriented green manufacturing technology of special membrane Chinese medicines and its special equipment integration research國家重點研發計劃中醫藥現代化重點專項：質量評價導向的特種膜中藥綠色制造技術及其專程裝備集成研究，2019
  • Macao Science and Technology Development Fund Key R & D Funding Program: Development of International Standards for Traditional Chinese Medicines, 2020-2022
    澳門科技發展基金重點研發資助計劃：中藥國際標準的研究與制訂，2020-2022
  • Guangdong Province Key Field R & D Program “Lingnan Traditional Chinese Medicine Modernization” Key Special Project: Research on International Standards of Eight Traditional Chinese Medicines with Guangdong Characteristics, 2020-2021
    廣東省重點領域研發計畫“嶺南中醫藥現代化”重點專項：八種廣東特色中藥國際標準研究，2020-2021
  • National Natural Science Foundation of China: “Saccharide mapping” to study the active structural unit of polysaccharides in traditional Chinese medicines-Hericium erinaceus polysaccharide
    國家自然科學基金：“糖譜法”研究中藥多糖活性結構單元—猴頭菇多糖為例，2017-2020
  • Macao Science and Technology Development Fund: Research on Improving Quality Standards of Wolfberry in “Chinese Pharmacopoeia”, 2019-2020
    澳門科技發展基金：《中國藥典》枸杞質量標準提升研究，2019-2020
  • Macao Science and Technology Development Fund: “Saccharide mapping” combined with receptor fishing techniques to study active units and structural characteristics of polysaccharides from traditional Chinese medicines, 2017-2019
    澳門科技發展基金：“糖譜法”結合受體垂釣技術研究中藥多糖活性部位與結構特征，2017-2019
  • Guangzhou Foreign Science and Technology Cooperation Program: Based on “receptor fishing technology” to optimize the formula for external use of psoriasis and its preclinical research, 2018-2020
    廣州市對外科技合作計劃：基於“受體垂釣技術”優選銀屑病外用方及其臨床前研究，2018-2020

  • Li SP, Macao Science and Technology Award 2020 – Third Class Prize in Natural Science Award (1st applicant)
  • Li SP, Macao Science and Technology Award 2018 – Second Class Prize in Advanced Science & Technology Award (1st applicant)
  • Li SP, Macao Science and Technology Award 2016 – Second Class Prize in Natural Science Award (2nd applicant)
  • 1 PhD student, Macao Science and Technology Award 2020 – Scientific and Technological R&D Award for postgraduates (total 20 awardee)
  • 2 PhD students, Macao Science and Technology Award 2016 – Scientific and Technological R&D Award for postgraduates (total 20 awardee)
  • 2 PhD students, Macao Science and Technology Award 2014 – Scientific and Technological R&D Award for postgraduates (total 20 awardee)
  • 2 PhD students, Macao Science and Technology Award 2012 – Scientific and Technological R&D Award for postgraduates (total 20 awardee)
  • 1 master student, Macao Science and Technology Award 2012 – Scientific and Technological R&D Award for postgraduates (total 10 awardee)

  1. 澳大發佈新書《澳門蕈菌》 15年匠心編著填補空白
  2. 國際學刊首以澳大博雅之璧作封面設計
  3. 中華中醫藥傑出貢獻獎
  4. 《藥物分析雜誌》普析通用杯第八屆優秀論文一等獎-2018
  5. 75% of Reishi supplements don’t actually contain Reishi mushroom
  6. 澳大“糖譜法”技術鑒定美國保健品質量
  7. 澳門大學參與國際中藥標準制訂 獲美國藥典委員會認可
  8. 澳門大學“糖分析”論文獲中國藥學會一等獎
  9. 《中國藥學雜誌》島津杯全國藥物分析優秀論文-2017

Selected Books

  1. 李紹平，趙靜. 《澳門蕈菌》，科學出版社，2019，北京
  2. 李紹平, 副主編，《中藥分析學》(全國高等醫藥院校藥學類規劃教材)，醫藥科技出版社，北京,2015(第2版),2019（第3版）
  3. Li, S.P., Wang, Y.T. (2008) Pharmacological Activity Based Quality Control of Chinese Herbs. Nova Science Publishers, Inc. New York.
  4. 李紹平，王一濤. 主編. 《常用中藥色譜分析方法》，澳門大學，澳門，
  5. 李紹平, 副主編，《現代生藥學》，科學出版社，北京，

Selected Journal Articles (*Corresponding Author)

  1. Zhao, S.C. Ma, S.P. Li* Advanced strategies for quality control of Chinese medicines, J. Pharm. Biomed. Anal. 2018, 147: 473-478.
  2. Li, S.P.*, Zhao, J., Yang, B. Strategies for quality control of Chinese medicines. Pharm. Biomed. Anal. 2011, 55: 802-809.
  3. Zhao, J.; Deng, Y.; Li, S. P.* Advanced analysis of polysaccharides, novel functional components in food and medicine dual purposes Chinese herbs. TrAC Trends in Analytical Chemistry 2017, 96: 138-150.
  4. Li, S. P.*, Wu, D. T., Lv, G. P., Zhao, J. Carbohydrates analysis in herbal glycomics. TrAC Trends in Analytical Chemistry 2013, 52: 155-169.
  5. Deng, Y., Lam, S. C., Zhao, J., Li, S. P.* Quantitative analysis of flavonoids and phenolic acid in Coreopsis tinctoria by capillary zone electrophoresis. Electrophoresis 2017, 38: 2654-2661. (Cover Story)
  6. Cheong, K.L., Wu, D.T., Zhao, J., Li, S. P.* A rapid and accurate method for the quantitative estimation of natural polysaccharides and their fractions using high performance size exclusion chromatography coupled with multi-angle laser light scattering and refractive index detector. Chromatogr. A 2015, 1400: 98-106.
  7. Wang, L. Y.; Cheong, K. L.; Wu, D. T.; Meng, L. Z.; Zhao, J.; Li, S. P.* Fermentation optimization for the production of bioactive polysaccharides from Cordyceps sinensis fungus UM01. Int. J. Biol. Macromol. 2015, 79: 180-185.
  8. Lv, G. P.; Hu, D. J.; Cheong, K. L.; Li, Z. Y.; Qing, X. M.; Zhao, J.; Li, S. P.* Decoding glycome of Astragalus membranaceus based on pressurized liquid extraction, microwave-assisted hydrolysis and chromatographic analysis. Chromatogr. A 2015, 1409: 19-29.
  9. Lin, P. C.; Wu, D. T.; Xie, J.; Zhao, J.; Li, S. P.* Characterization and comparison of bioactive polysaccharides from the tubers of Gymnadenia conopsea. Food Hydrocolloids 2015, 43: 199-206.
  10. Cheong, K. L.; Wu, D. T.; Zhao, J.; Li, S. P.* A rapid and accurate method for the quantitative estimation of natural polysaccharides and their fractions using high performance size exclusion chromatography coupled with multi-angle laser light scattering and refractive index detector. Chromatogr. A 2015, 1400: 98-106.
  11. Jin, H. R., Liao, Y., Li, X., Zhang, Z,, Zhao, Z., Wang. C. Z., Huang, W. H., Li, S. P.*, Yuan, C. S., Du, W. Anticancer compound Oplopantriol A kills cancer cells through inducing ER stress and BH3 proteins Bim and Noxa. Cell Death Dis. 2014, 5, e1190.
  12. Li, D. Q., Zhao, J., Li, S. P.* High-performance liquid chromatography coupled with post-column dual-bioactivity assay for simultaneous screening of xanthine oxidase inhibitors and free radical scavengers from complex mixture. Chromatogr. A 2014, 1345: 50-56.
  13. Li, J., Hu, D. J., Zong, W., Lv, G. P., Zhao, J., Li, S. P.* Determination of Inulin-type Fructooligosaccharides in Edible Plants by High-Performance Liquid Chromatography with Charged Aerosol Detector. J. Agric. Food Chem. 2014, 62: 7707-7713.
  14. Meng,L. Z., Feng, K., Wang, L. Y., Cheong, K. L., Nie, H., Zhao, J., Li, S. P.* Activation of mouse macrophages and dendritic cells induced by polysaccharides from a novel Cordyceps sinensis fungus UM01. J. Func. Foods 2014, 9: 242-253.
  15. Li, S. P.*, Qiao, C. F., Chen, Y. W., Zhao, J., Cui, X. M., Zhang, Q. W., Liu, X. M., Hu, D. J. A novel strategy with standardized reference extract qualification and single compound quantitative evaluation for quality control of Panax notoginseng used as a functional food. Chromatogr. A 2013, 1313: 302-307.
  16. Zhao, J., Deng, J. W., Chen, Y. W., Li, S. P.* Advanced phytochemical analysis of herbal tea in China. Chromatogr. A 2013, 1313: 2-23.
  17. Li, J., Cheong, K. L., Zhao, J., Hu, D. J., Chen, X. Q., Qiao, C. F., Zhang, Q. W., Chen, Y. W., Li, S. P.* Preparation of inulin-type fructooligosaccharides using fast protein liquid chromatography coupled with refractive index detection. Chromatogr. A 2013, 1308: 52-57.
  18. Li, J., Liu, X. M., Zhou, B., Zhao, J., Li, S. P.* Determination of Fructooligosaccharides in Burdock Using HPLC and Microwave-Assisted Extraction. Agric. Food Chem. 2013, 61: 5888-5892.
  19. Wu, D. T., Cheong, K. L., Wang, L. Y., Lv, G. P., Ju, Y. J., Feng, K., Zhao, J., Li, S. P.* Characterization and discrimination of polysaccharides from different species of Cordyceps using saccharide mapping based on PACE and HPTLC. Polym. 2014, 103: 100-109.
  20. Li, D. Q., Zhao, J., Li, S. P.*, Zhang, Q. W., Discovery of xanthine oxidase inhibitors from a complex mixture using an online, restricted-access material coupled with column-switching liquid chromatography with a diode-array detection system. Bioanal. Chem. 2014, 406: 1975-1984.
  21. Wu, D. T., Xie, J., Hu, D. J., Zhao, J., Li, S. P.* Characterization of polysaccharides from Ganoderma spp. using saccharide mapping. Polym. 2013, 97: 398-405.
  22. Han, D. Q., Zhao, J., Xu, J., Peng, H. S., Chen, X. J., Li, S. P.* Quality evaluation of Polygonum multiflorum in China based on HPLC analysis of hydrophilic bioactive compounds and chemometrics. Pharm. Biomed. Anal. 2013, 72: 223-230.
  23. Chen, Y. W., Hu, D. J., Cheong, K. L., Li, J., Xie, J., Zhao, J., Li, S. P.* Quality evaluation of lentinan injection produced in China. Pharm. Biomed. Anal. 2013, 78-79: 176-182.
  24. Meng, L. Z., Lin, B. Q., Wang, B., Feng, K., Hu, D. J., Wang, L. Y., Cheong, K. L., Zhao, J., Li, S. P.* Mycelia extracts of fungal strains isolated from Cordyceps sinensis differently enhance the function of RAW 264.7 macrophages. Ethnopharmacol. 2013, 148: 818-825.