Wai San CHEANG 鄭慧珊
Assistant Professor

Academic Qualifications

  • B.Sc. (Hon), The Chinese University of Hong Kong, HK
  • Ph.D., The Chinese University of Hong Kong, HK
  • Postdoctoral training, University of California, San Diego, USA


Research Interests

  • Molecular pharmacology of Chinese herbs and natural plants
  • Vascular dysfunction and metabolic disorders

We are looking for young talents who are interested in our research projects on vascular pharmacology to join us. For further details, please contact Dr. Cheang at annacheang@um.edu.mo

Selected Publications

  1. Cheang WS, Wong WT, Zhao L, Xu J, Wang L, Lau CW, Chen ZY, Ma RCW, Xu A, Wang N, Tian XY, Huang Y. PPARδ is required for exercise to attenuate endoplasmic reticulum stress and endothelial dysfunction in diabetic mice. Diabetes (2017) 66(2):519-28. (Impact factor: 8.784)
  2. Chen L, Teng H, Xie Z, Cheang WS, Skalicka-Woniak K, Georgiev MI, Xiao J. Modifications of dietary flavonoids towards improved bioactivity: An update on structure-activity relationship. Critical Reviews in Food Science and Nutrition (2016) (In press) (Impact factor: 5.492)
  3. Tian XY, Wong WT, Lau CW, Wang Y, Cheang WS, Liu J, Lu Y, Huang H, Xia Y, Chen Z, Mok C, Lau C, Huang Y. Melamine impairs renal and vascular function in rats. Scientific Reports (2016) 6:28041. (Impact factor: 5.228)
  4. Cheang WS, Ngai, CY, Tam YY, Tian XY, Wong WT, Zhang Y, Lau CW, Chen Z, Bian ZX, Huang Y, Leung FP. Black tea protects against hypertension-associated endothelial dysfunction through alleviation of endoplasmic reticulum stress. Scientific Reports (2015) 5:10340. (Impact factor: 5.228)
  5. Zhang Y, Liu J, Luo JY, Tian XY, Cheang WS, Xu J, Lau CW, Wang L, Wong WT, Wong CM, Lan HY, Yao X, Raizada MK, Huang Y. Upregulation of angiotensin (1-7)-mediated signaling preserves endothelial function through reducing oxidative stress in diabetes. Antioxidants & Redox Signaling (2015) 23(11):880-92. (Impact factor: 7.093)
  6. Cheang WS, Tian XY, Wong WT, Huang Y. Peroxisome proliferator-activated receptors in cardiovascular diseases: experimental benefits and clinical challenges. British Journal of Pharmacology (2015) 172(23):5512-22. (Impact factor: 5.259)
  7. Wang X, *Cheang WS, Yang H, Xiao L, Lai B, Zhang M, Ni J, Luo Z, Zhang Z, Huang Y, Wang N. Nuciferine relaxes rat mesenteric arteries through endothelium-dependent and independent mechanisms. British Journal of Pharmacology (2015) 172(23):5609-18. (*Co-first author) (Impact factor: 5.259)
  8. Cheang WS, Tian XY, Wong WT, Lee SS, Chen ZY, Yao X, Wang N, Huang Y. Metformin protects endothelial function in diet-induced obese mice by inhibition of endoplasmic reticulum stress through 5’ adenosine monophosphate-activated protein kinase-peroxisome proliferator-activated receptor δ pathway. Arteriosclerosis, Thrombosis and Vascular Biology (2014) 34(4):830-6. (Impact factor: 5.969)
  9. Zhang Y, Liu J, Tian XY, Wong WT, Chen Y, Wang L, Luo JY,Cheang WS, Lau CW, Kwan KM, Wang N, Yao X & Huang Y. Inhibition of bone morphogenic protein-4 restores endothelial function in db/db diabetic mice. Arteriosclerosis, Thrombosis and Vascular Biology (2014) 34(1):152-9. (Impact factor: 5.969)
  10. Tian XY, Wong WT, Wang N, Lu Y, Cheang WS, Liu J, Liu L, Liu Y, Lee SS, Chen ZY, Cooke JP, Yao X, Huang Y. PPARδ activation protects endothelial function in diabetic mice. Diabetes (2012) 61(12):3285-93. (Impact factor: 8.784)
  11. Tian XY, Wong WT, Xu A, Lu Y, Zhang Y, Wang L, Cheang WS, Wang Y, Yao X, Huang Y. Uncoupling protein-2 protects endothelial function in diet-induced obese mice. Circulation Research (2012) 110(9):1211-6. (Impact factor: 11.551)
  12. Cheang WS, Wong WT, Tian XY, Yang Q, Lee HK, He GW, Yao X, Huang Y. Endothelial nitric oxide synthase enhancer reduces oxidative stress and restores endothelial function in db/db mice. Cardiovascular Research (2011) 92(2):267-75. (Impact factor: 5.465)

Social Service

  • Editorial Board Member, SM Vascular Medicine (2016-present)
  • Editorial Board Member, Food Science and Nutrition Technology (2016-present)

Contact Details

Institute of Chinese Medical Sciences
University of Macau
Macao, China

Room 8004, N22 Research Building
Telephone: (853) 8822-4914
Fax: (853) 2884-1358
E-mail: annacheang@um.edu.mo