Shaoping LI

Shaoping LI  李紹平
Distinguished Professor,
Deputy Director of State Key Laboratory of Quality Research in Chinese Medicine

Academic Qualifications

  • MSc, PhD, China Pharmaceutical University

Teaching

M.Sc. Courses

  1. Quality Control of Chinese Medicine (CMED716)

PhD Course

  1. Quality Research of Chinese Medicine (CMED809)
  2. Advanced Pharmaceutical Analysis (CMED822)

Research

Research Interests

  • Herbal glycol-analysis, especially saccharide mapping.
  • Standard development of Chinese medicines.
  • Development of quality control methods, including HPLC, LC-MS, CE, CEC and GC-MS, for Chinese medicines.
  • Culture, fermentation, active ingredients and quality control of medicinal mushroom, such as Cordyceps spp., Ganoderma spp..

Selected Awards and Honors

  • Li SP, Macao Science and Technology Award 2018 – Second Class Prize in Advanced Science & Technology Award (1st applicant)
  • Li SP, Macao Science and Technology Award 2016 – Second Class Prize in Natural Science Award (2nd applicant)
  • 2 PhD students, Macao Science and Technology Award 2016 – Scientific and Technological R&D Award for postgraduates (total 20 awardee)
  • 2 PhD students, Macao Science and Technology Award 2014 – Scientific and Technological R&D Award for postgraduates (total 20 awardee)
  • 2 PhD students, Macao Science and Technology Award 2012 – Scientific and Technological R&D Award for postgraduates (total 20 awardee)
  • 1 master student, Macao Science and Technology Award 2012 – Scientific and Technological R&D Award for postgraduates (total 10 awardee)

 Selected News

  1. 國際學刊首以澳大博雅之璧作封面設計
  2. 中華中醫藥傑出貢獻獎
  3. 《藥物分析雜誌》普析通用杯第八屆優秀論文一等獎-2018
  4. 75% of Reishi supplements don’t actually contain Reishi mushroom
  5. 澳大“糖譜法”技術鑒定美國保健品質量
  6. 澳門大學參與國際中藥標準制訂 獲美國藥典委員會認可
  7. 澳門大學“糖分析”論文獲中國藥學會一等獎
  8. 《中國藥學雜誌》島津杯全國藥物分析優秀論文-2017

We are looking for Post-doctor, PhD students and master students who are interested in herbal glycochemistry, glycobiology, instrumental analysis and Chinese medicines. For further information, please contact Prof. Li (spli@um.edu.mo).


Publications (>300 peer refereed articles)

Selected Books

  1. 李紹平, 副主編,中藥分析學(全國高等醫藥院校藥學類規劃教材),醫藥科技出版社,北京,2015
  2. Li, S.P., Wang, Y.T. (2008) Pharmacological Activity Based Quality Control of Chinese Herbs. Nova Science Publishers, Inc. New York.
  3. 李紹平,王一濤. 主編. 《常用中藥色譜分析方法》,澳門大學,澳門,2009.
  4. 李紹平, 副主編,《現代生藥學》,科學出版社,北京,2006.

Selected Journal Articles (* Corresponding Author)

  1. J. Zhao, S.C. Ma, S.P. Li* Advanced strategies for quality control of Chinese medicines, J. Pharm. Biomed. Anal. 2018, 147: 473-478.
  2. Li, S.P.*, Zhao, J., Yang, B. Strategies for quality control of Chinese medicines. J. Pharm. Biomed. Anal. 2011, 55: 802-809.
  3. Zhao, J.; Deng, Y.; Li, S. P.* Advanced analysis of polysaccharides, novel functional components in food and medicine dual purposes Chinese herbs. TrAC Trends in Analytical Chemistry 2017, 96: 138-150.
  4. Li, S. P.*, Wu, D. T., Lv, G. P., Zhao, J. Carbohydrates analysis in herbal glycomics. TrAC Trends in Analytical Chemistry 2013, 52: 155-169.
  5. Wu, D. T., Deng, Y., Chen, L. X., Zhao, J., Bzhelyansky, A., Li, S. P.* Evaluation on quality consistency of Ganoderma lucidum dietary supplements collected in the United States. Sci. Rep. 2017, 7: 7792.
  6. Deng, Y., Lam, S. C., Zhao, J., Li, S. P.* Quantitative analysis of flavonoids and phenolic acid in Coreopsis tinctoria Nutt. by capillary zone electrophoresis. Electrophoresis 2017, 38: 2654-2661. (Cover Story)
  7. Wu, D. T., Lv, G. P., Zheng, J., Li, Q., Ma, S. C., Li, S. P.*, Zhao, J. Cordyceps collected from Bhutan, an appropriate alternative of Cordyceps sinensis, Sci. Rep. 2016, 6: 37668.
  8. Cheong, K.L., Wu, D.T., Zhao, J., Li, S. P.* A rapid and accurate method for the quantitative estimation of natural polysaccharides and their fractions using high performance size exclusion chromatography coupled with multi-angle laser light scattering and refractive index detector. J. Chromatogr. A 2015, 1400: 98-106.
  9. Wang, L. Y.; Cheong, K. L.; Wu, D. T.; Meng, L. Z.; Zhao, J.; Li, S. P.* Fermentation optimization for the production of bioactive polysaccharides from Cordyceps sinensis fungus UM01. Int. J. Biol. Macromol. 2015, 79: 180-185.
  10. Lv, G. P.; Hu, D. J.; Cheong, K. L.; Li, Z. Y.; Qing, X. M.; Zhao, J.; Li, S. P.* Decoding glycome of Astragalus membranaceus based on pressurized liquid extraction, microwave-assisted hydrolysis and chromatographic analysis. J. Chromatogr. A 2015, 1409: 19-29.
  11. Lin, P. C.; Wu, D. T.; Xie, J.; Zhao, J.; Li, S. P.* Characterization and comparison of bioactive polysaccharides from the tubers of Gymnadenia conopsea. Food Hydrocolloids 2015, 43: 199-206.
  12. Cheong, K. L.; Wu, D. T.; Zhao, J.; Li, S. P.* A rapid and accurate method for the quantitative estimation of natural polysaccharides and their fractions using high performance size exclusion chromatography coupled with multi-angle laser light scattering and refractive index detector. J. Chromatogr. A 2015, 1400: 98-106.
  13. Jin, H. R., Liao, Y., Li, X., Zhang, Z,, Zhao, Z., Wang. C. Z., Huang, W. H., Li, S. P.*, Yuan, C. S., Du, W. Anticancer compound Oplopantriol A kills cancer cells through inducing ER stress and BH3 proteins Bim and Noxa. Cell Death Dis. 2014, 5, e1190.
  14. Li, D. Q., Zhao, J., Li, S. P.* High-performance liquid chromatography coupled with post-column dual-bioactivity assay for simultaneous screening of xanthine oxidase inhibitors and free radical scavengers from complex mixture. J. Chromatogr. A 2014, 1345: 50-56.
  15. Li, J., Hu, D. J., Zong, W. R., Lv, G. P., Zhao, J., Li, S. P.* Determination of Inulin-type Fructooligosaccharides in Edible Plants by High-Performance Liquid Chromatography with Charged Aerosol Detector. J. Agric. Food Chem. 2014, 62: 7707-7713.
  16. Meng, L. Z., Feng, K., Wang, L. Y., Cheong, K. L., Nie, H., Zhao, J., Li, S. P.* Activation of mouse macrophages and dendritic cells induced by polysaccharides from a novel Cordyceps sinensis fungus UM01. J. Func. Foods 2014, 9: 242-253.
  17. Li, S. P.*, Qiao, C. F., Chen, Y. W., Zhao, J., Cui, X. M., Zhang, Q. W., Liu, X. M., Hu, D. J. A novel strategy with standardized reference extract qualification and single compound quantitative evaluation for quality control of Panax notoginseng used as a functional food. J. Chromatogr. A 2013, 1313: 302-307.
  18. Zhao, J., Deng, J. W., Chen, Y. W., Li, S. P.* Advanced phytochemical analysis of herbal tea in China. J. Chromatogr. A 2013, 1313: 2-23.
  19. Li, J., Cheong, K. L., Zhao, J., Hu, D. J., Chen, X. Q., Qiao, C. F., Zhang, Q. W., Chen, Y. W., Li, S. P.* Preparation of inulin-type fructooligosaccharides using fast protein liquid chromatography coupled with refractive index detection. J. Chromatogr. A 2013, 1308: 52-57.
  20. Li, J., Liu, X. M., Zhou, B., Zhao, J., Li, S. P.* Determination of Fructooligosaccharides in Burdock Using HPLC and Microwave-Assisted Extraction. J. Agric. Food Chem. 2013, 61: 5888-5892.
  21. Wu, D. T., Cheong, K. L., Wang, L. Y., Lv, G. P., Ju, Y. J., Feng, K., Zhao, J., Li, S. P.* Characterization and discrimination of polysaccharides from different species of Cordyceps using saccharide mapping based on PACE and HPTLC. Carbohydr. Polym. 2014, 103: 100-109.
  22. Li, D. Q., Zhao, J., Li, S. P.*, Zhang, Q. W., Discovery of xanthine oxidase inhibitors from a complex mixture using an online, restricted-access material coupled with column-switching liquid chromatography with a diode-array detection system. Anal. Bioanal. Chem. 2014, 406: 1975-1984.
  23. Wu, D. T., Xie, J., Hu, D. J., Zhao, J., Li, S. P.* Characterization of polysaccharides from Ganoderma spp. using saccharide mapping. Carbohydr. Polym. 2013, 97: 398-405.
  24. Han, D. Q., Zhao, J., Xu, J., Peng, H. S., Chen, X. J., Li, S. P.* Quality evaluation of Polygonum multiflorum in China based on HPLC analysis of hydrophilic bioactive compounds and chemometrics. J. Pharm. Biomed. Anal. 2013, 72: 223-230.
  25. Chen, Y. W., Hu, D. J., Cheong, K. L., Li, J., Xie, J., Zhao, J., Li, S. P.* Quality evaluation of lentinan injection produced in China. J. Pharm. Biomed. Anal. 2013, 78-79: 176-182.
  26. Meng, L. Z., Lin, B. Q., Wang, B., Feng, K., Hu, D. J., Wang, L. Y., Cheong, K. L., Zhao, J., Li, S. P.* Mycelia extracts of fungal strains isolated from Cordyceps sinensis differently enhance the function of RAW 264.7 macrophages. J. Ethnopharmacol. 2013, 148: 818-825.

Qualifications (Partial)


Contact Details

Room 6008, N22
Institute of Chinese Medical Sciences  (ICMS)
University of Macau
Avenida da Universidade, Taipa,
Tel.: +853-88224692
E-mail:spli@um.edu.mo